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A toxicogenomic approach for the risk assessment of the food contaminant acetamide.
Nault R, Bals B, Teymouri F, Black MB, Andersen ME, McMullen PD, Krishnan S, Kuravadi N, Paul N, Kumar S, Kannan K, Jayachandra KC, Alagappan L, Patel BD, Bogen KT, Gollapudi BB, Klaunig JE, Zacharewski TR, Bringi V. Nault R, et al. Among authors: mcmullen pd. Toxicol Appl Pharmacol. 2020 Feb 1;388:114872. doi: 10.1016/j.taap.2019.114872. Epub 2019 Dec 24. Toxicol Appl Pharmacol. 2020. PMID: 31881176 Free PMC article.
A map of the PPARα transcription regulatory network for primary human hepatocytes.
McMullen PD, Bhattacharya S, Woods CG, Sun B, Yarborough K, Ross SM, Miller ME, McBride MT, LeCluyse EL, Clewell RA, Andersen ME. McMullen PD, et al. Chem Biol Interact. 2014 Feb 25;209:14-24. doi: 10.1016/j.cbi.2013.11.006. Epub 2013 Nov 22. Chem Biol Interact. 2014. PMID: 24269660 Free article.
Developing tools for defining and establishing pathways of toxicity.
Andersen ME, McMullen PD, Krewski D. Andersen ME, et al. Among authors: mcmullen pd. Arch Toxicol. 2015 May;89(5):809-12. doi: 10.1007/s00204-015-1512-y. Epub 2015 Apr 8. Arch Toxicol. 2015. PMID: 25851822 Free PMC article. No abstract available.
Information-dependent enrichment analysis reveals time-dependent transcriptional regulation of the estrogen pathway of toxicity.
Pendse SN, Maertens A, Rosenberg M, Roy D, Fasani RA, Vantangoli MM, Madnick SJ, Boekelheide K, Fornace AJ, Odwin SA, Yager JD, Hartung T, Andersen ME, McMullen PD. Pendse SN, et al. Among authors: mcmullen pd. Arch Toxicol. 2017 Apr;91(4):1749-1762. doi: 10.1007/s00204-016-1824-6. Epub 2016 Sep 3. Arch Toxicol. 2017. PMID: 27592001 Free PMC article.
Pathway Based Toxicology and Fit-for-Purpose Assays.
Clewell RA, McMullen PD, Adeleye Y, Carmichael PL, Andersen ME. Clewell RA, et al. Among authors: mcmullen pd. Adv Exp Med Biol. 2016;856:205-230. doi: 10.1007/978-3-319-33826-2_8. Adv Exp Med Biol. 2016. PMID: 27671724
Combining transcriptomics and PBPK modeling indicates a primary role of hypoxia and altered circadian signaling in dichloromethane carcinogenicity in mouse lung and liver.
Andersen ME, Black MB, Campbell JL, Pendse SN, Clewell HJ III, Pottenger LH, Bus JS, Dodd DE, Kemp DC, McMullen PD. Andersen ME, et al. Among authors: mcmullen pd. Toxicol Appl Pharmacol. 2017 Oct 1;332:149-158. doi: 10.1016/j.taap.2017.04.002. Epub 2017 Apr 7. Toxicol Appl Pharmacol. 2017. PMID: 28392392 Free article.
52 results