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Knockdown of Virus Antigen Expression Increases Therapeutic Vaccine Efficacy in High-Titer Hepatitis B Virus Carrier Mice.
Michler T, Kosinska AD, Festag J, Bunse T, Su J, Ringelhan M, Imhof H, Grimm D, Steiger K, Mogler C, Heikenwalder M, Michel ML, Guzman CA, Milstein S, Sepp-Lorenzino L, Knolle P, Protzer U. Michler T, et al. Among authors: festag j. Gastroenterology. 2020 May;158(6):1762-1775.e9. doi: 10.1053/j.gastro.2020.01.032. Epub 2020 Jan 28. Gastroenterology. 2020. PMID: 32001321
T-cell engager antibodies enable T cells to control HBV infection and to target HBsAg-positive hepatoma in mice.
Quitt O, Luo S, Meyer M, Xie Z, Golsaz-Shirazi F, Loffredo-Verde E, Festag J, Bockmann JH, Zhao L, Stadler D, Chou WM, Tedjokusumo R, Wettengel JM, Ko C, Noeßner E, Bulbuc N, Shokri F, Lüttgau S, Heikenwälder M, Bohne F, Moldenhauer G, Momburg F, Protzer U. Quitt O, et al. Among authors: festag j. J Hepatol. 2021 Nov;75(5):1058-1071. doi: 10.1016/j.jhep.2021.06.022. Epub 2021 Jun 23. J Hepatol. 2021. PMID: 34171437
Hepatitis B virus envelope proteins can serve as therapeutic targets embedded in the host cell plasma membrane.
Zhao L, Chen F, Quitt O, Festag M, Ringelhan M, Wisskirchen K, Festag J, Yakovleva L, Sureau C, Bohne F, Aichler M, Bruss V, Shevtsov M, van de Klundert M, Momburg F, Möhl BS, Protzer U. Zhao L, et al. Among authors: festag j. Cell Microbiol. 2021 Dec;23(12):e13399. doi: 10.1111/cmi.13399. Epub 2021 Nov 22. Cell Microbiol. 2021. PMID: 34729894
Vector-Mediated Delivery of Human Major Histocompatibility Complex-I into Hepatocytes Enables Investigation of T Cell Receptor-Redirected Hepatitis B Virus-Specific T Cells in Mice, and in Macaque Cell Cultures.
Festag J, Festag MM, Asen T, Wettengel JM, Mück-Häusl MA, Abdulhaqq S, Stahl-Hennig C, Sacha JB, Burwitz BJ, Protzer U, Wisskirchen K. Festag J, et al. Hum Gene Ther. 2023 Dec;34(23-24):1204-1218. doi: 10.1089/hum.2023.035. Epub 2023 Dec 5. Hum Gene Ther. 2023. PMID: 37747811
14 results