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Defining a conformational ensemble that directs activation of PPARγ.
Chrisman IM, Nemetchek MD, de Vera IMS, Shang J, Heidari Z, Long Y, Reyes-Caballero H, Galindo-Murillo R, Cheatham TE 3rd, Blayo AL, Shin Y, Fuhrmann J, Griffin PR, Kamenecka TM, Kojetin DJ, Hughes TS. Chrisman IM, et al. Nat Commun. 2018 May 4;9(1):1794. doi: 10.1038/s41467-018-04176-x. Nat Commun. 2018. PMID: 29728618 Free PMC article.
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ.
Brust R, Shang J, Fuhrmann J, Mosure SA, Bass J, Cano A, Heidari Z, Chrisman IM, Nemetchek MD, Blayo AL, Griffin PR, Kamenecka TM, Hughes TS, Kojetin DJ. Brust R, et al. Among authors: chrisman im. Nat Commun. 2018 Nov 8;9(1):4687. doi: 10.1038/s41467-018-07133-w. Nat Commun. 2018. PMID: 30409975 Free PMC article.
A structural mechanism of nuclear receptor biased agonism.
Nemetchek MD, Chrisman IM, Rayl ML, Voss AH, Hughes TS. Nemetchek MD, et al. Among authors: chrisman im. Proc Natl Acad Sci U S A. 2022 Dec 13;119(50):e2215333119. doi: 10.1073/pnas.2215333119. Epub 2022 Dec 5. Proc Natl Acad Sci U S A. 2022. PMID: 36469765 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 36784397