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Potassium channel dysfunction in human neuronal models of Angelman syndrome.
Sun AX, Yuan Q, Fukuda M, Yu W, Yan H, Lim GGY, Nai MH, D'Agostino GA, Tran HD, Itahana Y, Wang D, Lokman H, Itahana K, Lim SWL, Tang J, Chang YY, Zhang M, Cook SA, Rackham OJL, Lim CT, Tan EK, Ng HH, Lim KL, Jiang YH, Je HS. Sun AX, et al. Among authors: jiang yh. Science. 2019 Dec 20;366(6472):1486-1492. doi: 10.1126/science.aav5386. Science. 2019. PMID: 31857479 Free PMC article.
Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3.
Wang X, McCoy PA, Rodriguiz RM, Pan Y, Je HS, Roberts AC, Kim CJ, Berrios J, Colvin JS, Bousquet-Moore D, Lorenzo I, Wu G, Weinberg RJ, Ehlers MD, Philpot BD, Beaudet AL, Wetsel WC, Jiang YH. Wang X, et al. Among authors: jiang yh. Hum Mol Genet. 2011 Aug 1;20(15):3093-108. doi: 10.1093/hmg/ddr212. Epub 2011 May 10. Hum Mol Genet. 2011. PMID: 21558424 Free PMC article.
Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers.
Pappas AL, Bey AL, Wang X, Rossi M, Kim YH, Yan H, Porkka F, Duffney LJ, Phillips SM, Cao X, Ding JD, Rodriguiz RM, Yin HH, Weinberg RJ, Ji RR, Wetsel WC, Jiang YH. Pappas AL, et al. Among authors: jiang yh. JCI Insight. 2017 Oct 19;2(20):e92052. doi: 10.1172/jci.insight.92052. JCI Insight. 2017. PMID: 29046483 Free PMC article.
855 results