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First triclosan-based macrocyclic inhibitors of InhA enzyme.
Rodriguez F, Saffon N, Sammartino JC, Degiacomi G, Pasca MR, Lherbet C. Rodriguez F, et al. Among authors: saffon n. Bioorg Chem. 2020 Jan;95:103498. doi: 10.1016/j.bioorg.2019.103498. Epub 2019 Dec 6. Bioorg Chem. 2020. PMID: 31855823
Design, chemical synthesis of 3-(9H-fluoren-9-yl)pyrrolidine-2,5-dione derivatives and biological activity against enoyl-ACP reductase (InhA) and Mycobacterium tuberculosis.
Matviiuk T, Rodriguez F, Saffon N, Mallet-Ladeira S, Gorichko M, de Jesus Lopes Ribeiro AL, Pasca MR, Lherbet C, Voitenko Z, Baltas M. Matviiuk T, et al. Among authors: saffon n. Eur J Med Chem. 2013;70:37-48. doi: 10.1016/j.ejmech.2013.09.041. Epub 2013 Oct 2. Eur J Med Chem. 2013. PMID: 24140915
Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase I, II, and IX isoforms†.
Aimene Y, Eychenne R, Mallet-Ladeira S, Saffon N, Winum JY, Nocentini A, Supuran CT, Benoist E, Seridi A. Aimene Y, et al. Among authors: saffon n. J Enzyme Inhib Med Chem. 2019 Dec;34(1):773-782. doi: 10.1080/14756366.2019.1585835. J Enzyme Inhib Med Chem. 2019. PMID: 30843736 Free PMC article.
68 results