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New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties.
Estrada-Valencia M, Herrera-Arozamena C, Pérez C, Viña D, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada-Valencia M, et al. Among authors: vina d. J Enzyme Inhib Med Chem. 2019 Dec;34(1):712-727. doi: 10.1080/14756366.2019.1581184. J Enzyme Inhib Med Chem. 2019. PMID: 31852270 Free PMC article.
New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.
Estrada M, Herrera-Arozamena C, Pérez C, Viña D, Romero A, Morales-García JA, Pérez-Castillo A, Rodríguez-Franco MI. Estrada M, et al. Among authors: vina d. Eur J Med Chem. 2016 Oct 4;121:376-386. doi: 10.1016/j.ejmech.2016.05.055. Epub 2016 May 25. Eur J Med Chem. 2016. PMID: 27267007 Free article.
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Estrada Valencia M, Herrera-Arozamena C, de Andrés L, Pérez C, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Viña D, Yáñez M, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada Valencia M, et al. Among authors: vina d. Eur J Med Chem. 2018 Aug 5;156:534-553. doi: 10.1016/j.ejmech.2018.07.026. Epub 2018 Jul 11. Eur J Med Chem. 2018. PMID: 30025348 Free article.
66 results