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New flavonoid - N,N-dibenzyl(N-methyl)amine hybrids: Multi-target-directed agents for Alzheimer´s disease endowed with neurogenic properties.
Estrada-Valencia M, Herrera-Arozamena C, Pérez C, Viña D, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada-Valencia M, et al. Among authors: perez castillo a, perez c. J Enzyme Inhib Med Chem. 2019 Dec;34(1):712-727. doi: 10.1080/14756366.2019.1581184. J Enzyme Inhib Med Chem. 2019. PMID: 31852270 Free PMC article.
New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease.
López-Iglesias B, Pérez C, Morales-García JA, Alonso-Gil S, Pérez-Castillo A, Romero A, López MG, Villarroya M, Conde S, Rodríguez-Franco MI. López-Iglesias B, et al. Among authors: perez castillo a, perez c. J Med Chem. 2014 May 8;57(9):3773-85. doi: 10.1021/jm5000613. Epub 2014 Apr 28. J Med Chem. 2014. PMID: 24738476
New cinnamic - N-benzylpiperidine and cinnamic - N,N-dibenzyl(N-methyl)amine hybrids as Alzheimer-directed multitarget drugs with antioxidant, cholinergic, neuroprotective and neurogenic properties.
Estrada M, Herrera-Arozamena C, Pérez C, Viña D, Romero A, Morales-García JA, Pérez-Castillo A, Rodríguez-Franco MI. Estrada M, et al. Among authors: perez castillo a, perez c. Eur J Med Chem. 2016 Oct 4;121:376-386. doi: 10.1016/j.ejmech.2016.05.055. Epub 2016 May 25. Eur J Med Chem. 2016. PMID: 27267007 Free article.
Neurogenic and neuroprotective donepezil-flavonoid hybrids with sigma-1 affinity and inhibition of key enzymes in Alzheimer's disease.
Estrada Valencia M, Herrera-Arozamena C, de Andrés L, Pérez C, Morales-García JA, Pérez-Castillo A, Ramos E, Romero A, Viña D, Yáñez M, Laurini E, Pricl S, Rodríguez-Franco MI. Estrada Valencia M, et al. Among authors: perez castillo a, perez c. Eur J Med Chem. 2018 Aug 5;156:534-553. doi: 10.1016/j.ejmech.2018.07.026. Epub 2018 Jul 11. Eur J Med Chem. 2018. PMID: 30025348 Free article.
Resveratrol-Based MTDLs to Stimulate Defensive and Regenerative Pathways and Block Early Events in Neurodegenerative Cascades.
Herrera-Arozamena C, Estrada-Valencia M, López-Caballero P, Pérez C, Morales-García JA, Pérez-Castillo A, Sastre ED, Fernández-Mendívil C, Duarte P, Michalska P, Lombardía J, Senar S, León R, López MG, Rodríguez-Franco MI. Herrera-Arozamena C, et al. Among authors: perez castillo a, perez c. J Med Chem. 2022 Mar 24;65(6):4727-4751. doi: 10.1021/acs.jmedchem.1c01883. Epub 2022 Mar 4. J Med Chem. 2022. PMID: 35245051 Free PMC article.
3,530 results