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SPHK1 Is a Novel Target of Metformin in Ovarian Cancer.
Hart PC, Chiyoda T, Liu X, Weigert M, Curtis M, Chiang CY, Loth R, Lastra R, McGregor SM, Locasale JW, Lengyel E, Romero IL. Hart PC, et al. Mol Cancer Res. 2019 Apr;17(4):870-881. doi: 10.1158/1541-7786.MCR-18-0409. Epub 2019 Jan 17. Mol Cancer Res. 2019. PMID: 30655321 Free PMC article.
Loss of BRCA1 in the Cells of Origin of Ovarian Cancer Induces Glycolysis: A Window of Opportunity for Ovarian Cancer Chemoprevention.
Chiyoda T, Hart PC, Eckert MA, McGregor SM, Lastra RR, Hamamoto R, Nakamura Y, Yamada SD, Olopade OI, Lengyel E, Romero IL. Chiyoda T, et al. Among authors: hart pc. Cancer Prev Res (Phila). 2017 Apr;10(4):255-266. doi: 10.1158/1940-6207.CAPR-16-0281. Epub 2017 Mar 6. Cancer Prev Res (Phila). 2017. PMID: 28264838 Free PMC article.
Effective breast cancer combination therapy targeting BACH1 and mitochondrial metabolism.
Lee J, Yesilkanal AE, Wynne JP, Frankenberger C, Liu J, Yan J, Elbaz M, Rabe DC, Rustandy FD, Tiwari P, Grossman EA, Hart PC, Kang C, Sanderson SM, Andrade J, Nomura DK, Bonini MG, Locasale JW, Rosner MR. Lee J, et al. Among authors: hart pc. Nature. 2019 Apr;568(7751):254-258. doi: 10.1038/s41586-019-1005-x. Epub 2019 Mar 6. Nature. 2019. PMID: 30842661 Free PMC article.
NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.
Baig MS, Zaichick SV, Mao M, de Abreu AL, Bakhshi FR, Hart PC, Saqib U, Deng J, Chatterjee S, Block ML, Vogel SM, Malik AB, Consolaro ME, Christman JW, Minshall RD, Gantner BN, Bonini MG. Baig MS, et al. Among authors: hart pc. J Exp Med. 2015 Sep 21;212(10):1725-38. doi: 10.1084/jem.20140654. Epub 2015 Aug 31. J Exp Med. 2015. PMID: 26324446 Free PMC article.
SOD2 acetylation on lysine 68 promotes stem cell reprogramming in breast cancer.
He C, Danes JM, Hart PC, Zhu Y, Huang Y, de Abreu AL, O'Brien J, Mathison AJ, Tang B, Frasor JM, Wakefield LM, Ganini D, Stauder E, Zielonka J, Gantner BN, Urrutia RA, Gius D, Bonini MG. He C, et al. Among authors: hart pc. Proc Natl Acad Sci U S A. 2019 Nov 19;116(47):23534-23541. doi: 10.1073/pnas.1902308116. Epub 2019 Oct 7. Proc Natl Acad Sci U S A. 2019. PMID: 31591207 Free PMC article.
31 results