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Integrated Epigenome, Exome, and Transcriptome Analyses Reveal Molecular Subtypes and Homeotic Transformation in Uterine Fibroids.
George JW, Fan H, Johnson B, Carpenter TJ, Foy KK, Chatterjee A, Patterson AL, Koeman J, Adams M, Madaj ZB, Chesla D, Marsh EE, Triche TJ, Shen H, Teixeira JM. George JW, et al. Among authors: madaj zb. Cell Rep. 2019 Dec 17;29(12):4069-4085.e6. doi: 10.1016/j.celrep.2019.11.077. Cell Rep. 2019. PMID: 31851934 Free PMC article.
Genomic Status of MET Potentiates Sensitivity to MET and MEK Inhibition in NF1-Related Malignant Peripheral Nerve Sheath Tumors.
Peacock JD, Pridgeon MG, Tovar EA, Essenburg CJ, Bowman M, Madaj Z, Koeman J, Boguslawski EA, Grit J, Dodd RD, Khachaturov V, Cardona DM, Chen M, Kirsch DG, Maina F, Dono R, Winn ME, Graveel CR, Steensma MR. Peacock JD, et al. Cancer Res. 2018 Jul 1;78(13):3672-3687. doi: 10.1158/0008-5472.CAN-17-3167. Epub 2018 May 2. Cancer Res. 2018. PMID: 29720369 Free PMC article.
Mithramycin induces promoter reprogramming and differentiation of rhabdoid tumor.
Chasse MH, Johnson BK, Boguslawski EA, Sorensen KM, Rosien JE, Kang MH, Reynolds CP, Heo L, Madaj ZB, Beddows I, Foxa GE, Kitchen-Goosen SM, Williams BO, Triche TJ Jr, Grohar PJ. Chasse MH, et al. Among authors: madaj zb. EMBO Mol Med. 2021 Feb 5;13(2):e12640. doi: 10.15252/emmm.202012640. Epub 2020 Dec 17. EMBO Mol Med. 2021. PMID: 33332735 Free PMC article.
CDK9 Blockade Exploits Context-dependent Transcriptional Changes to Improve Activity and Limit Toxicity of Mithramycin for Ewing Sarcoma.
Flores G, Everett JH, Boguslawski EA, Oswald BM, Madaj ZB, Beddows I, Dikalov S, Adams M, Klumpp-Thomas CA, Kitchen-Goosen SM, Martin SE, Caplen NJ, Helman LJ, Grohar PJ. Flores G, et al. Among authors: madaj zb. Mol Cancer Ther. 2020 May;19(5):1183-1196. doi: 10.1158/1535-7163.MCT-19-0775. Epub 2020 Mar 3. Mol Cancer Ther. 2020. PMID: 32127464 Free PMC article.
53 results