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Effect of poly(propylene imine) glycodendrimers on β-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and Alzheimer's disease.
Klementieva O, Aso E, Filippini D, Benseny-Cases N, Carmona M, Juvés S, Appelhans D, Cladera J, Ferrer I. Klementieva O, et al. Among authors: appelhans d. Biomacromolecules. 2013 Oct 14;14(10):3570-80. doi: 10.1021/bm400948z. Epub 2013 Sep 26. Biomacromolecules. 2013. PMID: 24004423
Toxicity and proapoptotic activity of poly(propylene imine) glycodendrimers in vitro: considering their contrary potential as biocompatible entity and drug molecule in cancer.
Ziemba B, Franiak-Pietryga I, Pion M, Appelhans D, Muñoz-Fernández MÁ, Voit B, Bryszewska M, Klajnert-Maculewicz B. Ziemba B, et al. Among authors: appelhans d. Int J Pharm. 2014 Jan 30;461(1-2):391-402. doi: 10.1016/j.ijpharm.2013.12.011. Epub 2013 Dec 17. Int J Pharm. 2014. PMID: 24361266
Maltotriose-modified poly(propylene imine) Glycodendrimers as a potential novel platform in the treatment of chronic lymphocytic Leukemia. A proof-of-concept pilot study in the animal model of CLL.
Franiak-Pietryga I, Ziemba B, Sikorska H, Jander M, Kuncman W, Danilewicz M, Appelhans D, Lewkowicz P, Ostrowska K, Bryszewska M, Borowiec M. Franiak-Pietryga I, et al. Among authors: appelhans d. Toxicol Appl Pharmacol. 2020 Sep 15;403:115139. doi: 10.1016/j.taap.2020.115139. Epub 2020 Jul 17. Toxicol Appl Pharmacol. 2020. PMID: 32687837
165 results