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Tracking virus-specific CD4+ T cells during and after acute hepatitis C virus infection.
Lucas M, Ulsenheimer A, Pfafferot K, Heeg MH, Gaudieri S, Grüner N, Rauch A, Gerlach JT, Jung MC, Zachoval R, Pape GR, Schraut W, Santantonio T, Nitschko H, Obermeier M, Phillips R, Scriba TJ, Semmo N, Day C, Weber JN, Fidler S, Thimme R, Haberstroh A, Baumert TF, Klenerman P, Diepolder HM. Lucas M, et al. Among authors: thimme r. PLoS One. 2007 Jul 25;2(7):e649. doi: 10.1371/journal.pone.0000649. PLoS One. 2007. PMID: 17653276 Free PMC article.
Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level.
Neumann-Haefelin C, Frick DN, Wang JJ, Pybus OG, Salloum S, Narula GS, Eckart A, Biezynski A, Eiermann T, Klenerman P, Viazov S, Roggendorf M, Thimme R, Reiser M, Timm J. Neumann-Haefelin C, et al. Among authors: thimme r. J Virol. 2008 Apr;82(7):3438-51. doi: 10.1128/JVI.01700-07. Epub 2008 Jan 23. J Virol. 2008. PMID: 18216107 Free PMC article.
Escape from HLA-B*08-restricted CD8 T cells by hepatitis C virus is associated with fitness costs.
Salloum S, Oniangue-Ndza C, Neumann-Haefelin C, Hudson L, Giugliano S, aus dem Siepen M, Nattermann J, Spengler U, Lauer GM, Wiese M, Klenerman P, Bright H, Scherbaum N, Thimme R, Roggendorf M, Viazov S, Timm J. Salloum S, et al. Among authors: thimme r. J Virol. 2008 Dec;82(23):11803-12. doi: 10.1128/JVI.00997-08. Epub 2008 Sep 24. J Virol. 2008. PMID: 18815309 Free PMC article.
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.
Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R. Dazert E, et al. Among authors: thimme r. J Clin Invest. 2009 Feb;119(2):376-86. doi: 10.1172/JCI36587. Epub 2009 Jan 12. J Clin Invest. 2009. PMID: 19139562 Free PMC article.
Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.
Kasprowicz V, Kang YH, Lucas M, Schulze zur Wiesch J, Kuntzen T, Fleming V, Nolan BE, Longworth S, Berical A, Bengsch B, Thimme R, Lewis-Ximenez L, Allen TM, Kim AY, Klenerman P, Lauer GM. Kasprowicz V, et al. Among authors: thimme r. J Virol. 2010 Feb;84(3):1656-63. doi: 10.1128/JVI.01499-09. Epub 2009 Nov 11. J Virol. 2010. PMID: 19906915 Free PMC article.
Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.
Billerbeck E, Kang YH, Walker L, Lockstone H, Grafmueller S, Fleming V, Flint J, Willberg CB, Bengsch B, Seigel B, Ramamurthy N, Zitzmann N, Barnes EJ, Thevanayagam J, Bhagwanani A, Leslie A, Oo YH, Kollnberger S, Bowness P, Drognitz O, Adams DH, Blum HE, Thimme R, Klenerman P. Billerbeck E, et al. Among authors: thimme r. Proc Natl Acad Sci U S A. 2010 Feb 16;107(7):3006-11. doi: 10.1073/pnas.0914839107. Epub 2010 Jan 28. Proc Natl Acad Sci U S A. 2010. PMID: 20133607 Free PMC article.
432 results