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Curing hemophilia A by NHEJ-mediated ectopic F8 insertion in the mouse.
Zhang JP, Cheng XX, Zhao M, Li GH, Xu J, Zhang F, Yin MD, Meng FY, Dai XY, Fu YW, Yang ZX, Arakaki C, Su RJ, Wen W, Wang WT, Chen W, Choi H, Wang C, Gao G, Zhang L, Cheng T, Zhang XB. Zhang JP, et al. Among authors: zhang l, zhang xb, zhang f. Genome Biol. 2019 Dec 16;20(1):276. doi: 10.1186/s13059-019-1907-9. Genome Biol. 2019. PMID: 31843008 Free PMC article.
HDAC inhibitors improve CRISPR-mediated HDR editing efficiency in iPSCs.
Zhang JP, Yang ZX, Zhang F, Fu YW, Dai XY, Wen W, Zhang B, Choi H, Chen W, Brown M, Baylink D, Zhang L, Qiu H, Wang C, Cheng T, Zhang XB. Zhang JP, et al. Among authors: zhang l, zhang b, zhang xb, zhang f. Sci China Life Sci. 2021 Sep;64(9):1449-1462. doi: 10.1007/s11427-020-1855-4. Epub 2021 Jan 6. Sci China Life Sci. 2021. PMID: 33420926
PBX3 is essential for leukemia stem cell maintenance in MLL-rearranged leukemia.
Guo H, Chu Y, Wang L, Chen X, Chen Y, Cheng H, Zhang L, Zhou Y, Yang FC, Cheng T, Xu M, Zhang X, Zhou J, Yuan W. Guo H, et al. Among authors: zhang l, zhang x. Int J Cancer. 2017 Jul 15;141(2):324-335. doi: 10.1002/ijc.30739. Epub 2017 May 8. Int J Cancer. 2017. PMID: 28411381 Free article.
Safety and activity of an engineered, liver-tropic adeno-associated virus vector expressing a hyperactive Padua factor IX administered with prophylactic glucocorticoids in patients with haemophilia B: a single-centre, single-arm, phase 1, pilot trial.
Xue F, Li H, Wu X, Liu W, Zhang F, Tang D, Chen Y, Wang W, Chi Y, Zheng J, Du Z, Jiang W, Zhong C, Wei J, Zhu P, Fu R, Liu X, Chen L, Pei X, Sun J, Cheng T, Yang R, Xiao X, Zhang L. Xue F, et al. Among authors: zhang l, zhang f. Lancet Haematol. 2022 Jul;9(7):e504-e513. doi: 10.1016/S2352-3026(22)00113-2. Epub 2022 May 19. Lancet Haematol. 2022. PMID: 35598604 Clinical Trial.
Multilevel defects in the hematopoietic niche in essential thrombocythemia.
Sun T, Ju M, Dai X, Dong H, Gu W, Gao Y, Fu R, Liu X, Huang Y, Liu W, Ch Y, Wang W, Li H, Zhou Y, Shi L, Yang R, Zhang L. Sun T, et al. Among authors: zhang l. Haematologica. 2020 Mar;105(3):661-673. doi: 10.3324/haematol.2018.213686. Epub 2019 Jul 9. Haematologica. 2020. PMID: 31289202 Free PMC article.
124,936 results
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