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Acid Sphingomyelinase Deficiency Ameliorates Farber Disease.
Beckmann N, Becker KA, Kadow S, Schumacher F, Kramer M, Kühn C, Schulz-Schaeffer WJ, Edwards MJ, Kleuser B, Gulbins E, Carpinteiro A. Beckmann N, et al. Among authors: edwards mj. Int J Mol Sci. 2019 Dec 11;20(24):6253. doi: 10.3390/ijms20246253. Int J Mol Sci. 2019. PMID: 31835809 Free PMC article.
Regulation of hematogenous tumor metastasis by acid sphingomyelinase.
Carpinteiro A, Becker KA, Japtok L, Hessler G, Keitsch S, Požgajovà M, Schmid KW, Adams C, Müller S, Kleuser B, Edwards MJ, Grassmé H, Helfrich I, Gulbins E. Carpinteiro A, et al. Among authors: edwards mj. EMBO Mol Med. 2015 Jun;7(6):714-34. doi: 10.15252/emmm.201404571. EMBO Mol Med. 2015. PMID: 25851537 Free PMC article.
Antidepressants act by inducing autophagy controlled by sphingomyelin-ceramide.
Gulbins A, Schumacher F, Becker KA, Wilker B, Soddemann M, Boldrin F, Müller CP, Edwards MJ, Goodman M, Caldwell CC, Kleuser B, Kornhuber J, Szabo I, Gulbins E. Gulbins A, et al. Among authors: edwards mj. Mol Psychiatry. 2018 Dec;23(12):2324-2346. doi: 10.1038/s41380-018-0090-9. Epub 2018 Jul 23. Mol Psychiatry. 2018. PMID: 30038230 Free PMC article.
Stress induces major depressive disorder by a neutral sphingomyelinase 2-mediated accumulation of ceramide-enriched exosomes in the blood plasma.
Schumacher F, Carpinteiro A, Edwards MJ, Wilson GC, Keitsch S, Soddemann M, Wilker B, Kleuser B, Becker KA, Müller CP, Kornhuber J, Gulbins E. Schumacher F, et al. Among authors: edwards mj. J Mol Med (Berl). 2022 Oct;100(10):1493-1508. doi: 10.1007/s00109-022-02250-y. Epub 2022 Aug 31. J Mol Med (Berl). 2022. PMID: 36045177 Free PMC article.
Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.
Pewzner-Jung Y, Tavakoli Tabazavareh S, Grassmé H, Becker KA, Japtok L, Steinmann J, Joseph T, Lang S, Tuemmler B, Schuchman EH, Lentsch AB, Kleuser B, Edwards MJ, Futerman AH, Gulbins E. Pewzner-Jung Y, et al. Among authors: edwards mj. EMBO Mol Med. 2014 Sep;6(9):1205-14. doi: 10.15252/emmm.201404075. EMBO Mol Med. 2014. PMID: 25085879 Free PMC article.
Pseudomonas aeruginosa pyocyanin induces neutrophil death via mitochondrial reactive oxygen species and mitochondrial acid sphingomyelinase.
Managò A, Becker KA, Carpinteiro A, Wilker B, Soddemann M, Seitz AP, Edwards MJ, Grassmé H, Szabò I, Gulbins E. Managò A, et al. Among authors: edwards mj. Antioxid Redox Signal. 2015 May 1;22(13):1097-110. doi: 10.1089/ars.2014.5979. Epub 2015 Mar 18. Antioxid Redox Signal. 2015. PMID: 25686490 Free PMC article.
1,025 results