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Vitamin E sequestration by liver fat in humans.
Violet PC, Ebenuwa IC, Wang Y, Niyyati M, Padayatty SJ, Head B, Wilkins K, Chung S, Thakur V, Ulatowski L, Atkinson J, Ghelfi M, Smith S, Tu H, Bobe G, Liu CY, Herion DW, Shamburek RD, Manor D, Traber MG, Levine M. Violet PC, et al. Among authors: shamburek rd. JCI Insight. 2020 Jan 16;5(1):e133309. doi: 10.1172/jci.insight.133309. JCI Insight. 2020. PMID: 31821172 Free PMC article. Clinical Trial.
Vitamin E absorption and kinetics in healthy women, as modulated by food and by fat, studied using 2 deuterium-labeled α-tocopherols in a 3-phase crossover design.
Traber MG, Leonard SW, Ebenuwa I, Violet PC, Wang Y, Niyyati M, Padayatty S, Tu H, Courville A, Bernstein S, Choi J, Shamburek R, Smith S, Head B, Bobe G, Ramakrishnan R, Levine M. Traber MG, et al. Am J Clin Nutr. 2019 Nov 1;110(5):1148-1167. doi: 10.1093/ajcn/nqz172. Am J Clin Nutr. 2019. PMID: 31495886 Free PMC article. Clinical Trial.
Vitamin E treatment in NAFLD patients demonstrates that oxidative stress drives steatosis through upregulation of de-novo lipogenesis.
Podszun MC, Alawad AS, Lingala S, Morris N, Huang WA, Yang S, Schoenfeld M, Rolt A, Ouwerkerk R, Valdez K, Umarova R, Ma Y, Fatima SZ, Lin DD, Mahajan LS, Samala N, Violet PC, Levine M, Shamburek R, Gharib AM, Kleiner DE, Garraffo HM, Cai H, Walter PJ, Rotman Y. Podszun MC, et al. Redox Biol. 2020 Oct;37:101710. doi: 10.1016/j.redox.2020.101710. Epub 2020 Sep 1. Redox Biol. 2020. PMID: 32920226 Free PMC article.
Leptin decreases de novo lipogenesis in patients with lipodystrophy.
Baykal AP, Parks EJ, Shamburek R, Syed-Abdul MM, Chacko S, Cochran E, Startzell M, Gharib AM, Ouwerkerk R, Abd-Elmoniem KZ, Walter PJ, Walter M, Muniyappa R, Chung ST, Brown RJ. Baykal AP, et al. JCI Insight. 2020 Jul 23;5(14):e137180. doi: 10.1172/jci.insight.137180. JCI Insight. 2020. PMID: 32573497 Free PMC article.
Effect of extended-release niacin on serum lipids and on endothelial function in adults with sickle cell anemia and low high-density lipoprotein cholesterol levels.
Scoffone HM, Krajewski M, Zorca S, Bereal-Williams C, Littel P, Seamon C, Mendelsohn L, Footman E, Abi-Jaoudeh N, Sachdev V, Machado RF, Cuttica M, Shamburek R, Cannon RO 3rd, Remaley A, Minniti CP, Kato GJ. Scoffone HM, et al. Am J Cardiol. 2013 Nov 1;112(9):1499-504. doi: 10.1016/j.amjcard.2013.06.035. Epub 2013 Sep 13. Am J Cardiol. 2013. PMID: 24035168 Free PMC article. Clinical Trial.
Intracellular trafficking of the free cholesterol derived from LDL cholesteryl ester is defective in vivo in Niemann-Pick C disease: insights on normal metabolism of HDL and LDL gained from the NP-C mutation.
Shamburek RD, Pentchev PG, Zech LA, Blanchette-Mackie J, Carstea ED, VandenBroek JM, Cooper PS, Neufeld EB, Phair RD, Brewer HB Jr, Brady RO, Schwartz CC. Shamburek RD, et al. J Lipid Res. 1997 Dec;38(12):2422-35. J Lipid Res. 1997. PMID: 9458266 Free article.
80 results