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Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation.
Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Körbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Schuster S, Silbernagel G, Sester M, Sester U, Aßmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, März W, Böhm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U, Speer T. Zewinger S, et al. Among authors: fliser d. Nat Immunol. 2020 Jan;21(1):30-41. doi: 10.1038/s41590-019-0548-1. Epub 2019 Dec 9. Nat Immunol. 2020. PMID: 31819254
Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortality.
Schunk SJ, Kleber ME, März W, Pang S, Zewinger S, Triem S, Ege P, Reichert MC, Krawczyk M, Weber SN, Jaumann I, Schmit D, Sarakpi T, Wagenpfeil S, Kramann R, Boerwinkle E, Ballantyne CM, Grove ML, Tragante V, Pilbrow AP, Richards AM, Cameron VA, Doughty RN, Dubé MP, Tardif JC, Feroz-Zada Y, Sun M, Liu C, Ko YA, Quyyumi AA, Hartiala JA, Tang WHW, Hazen SL, Allayee H, McDonough CW, Gong Y, Cooper-DeHoff RM, Johnson JA, Scholz M, Teren A, Burkhardt R, Martinsson A, Smith JG, Wallentin L, James SK, Eriksson N, White H, Held C, Waterworth D, Trompet S, Jukema JW, Ford I, Stott DJ, Sattar N, Cresci S, Spertus JA, Campbell H, Tierling S, Walter J, Ampofo E, Niemeyer BA, Lipp P, Schunkert H, Böhm M, Koenig W, Fliser D, Laufs U, Speer T; eQTLGen consortium; BIOS consortium. Schunk SJ, et al. Among authors: fliser d. Eur Heart J. 2021 May 7;42(18):1742-1756. doi: 10.1093/eurheartj/ehab107. Eur Heart J. 2021. PMID: 33748830 Free PMC article.
Abnormal high-density lipoprotein induces endothelial dysfunction via activation of Toll-like receptor-2.
Speer T, Rohrer L, Blyszczuk P, Shroff R, Kuschnerus K, Kränkel N, Kania G, Zewinger S, Akhmedov A, Shi Y, Martin T, Perisa D, Winnik S, Müller MF, Sester U, Wernicke G, Jung A, Gutteck U, Eriksson U, Geisel J, Deanfield J, von Eckardstein A, Lüscher TF, Fliser D, Bahlmann FH, Landmesser U. Speer T, et al. Among authors: fliser d. Immunity. 2013 Apr 18;38(4):754-68. doi: 10.1016/j.immuni.2013.02.009. Epub 2013 Mar 7. Immunity. 2013. PMID: 23477738 Free article.
Innate immunity in CKD-associated vascular diseases.
Zewinger S, Schumann T, Fliser D, Speer T. Zewinger S, et al. Among authors: fliser d. Nephrol Dial Transplant. 2016 Nov;31(11):1813-1821. doi: 10.1093/ndt/gfv358. Epub 2015 Oct 9. Nephrol Dial Transplant. 2016. PMID: 26454223 Review.
Interleukin-1α Is a Central Regulator of Leukocyte-Endothelial Adhesion in Myocardial Infarction and in Chronic Kidney Disease.
Schunk SJ, Triem S, Schmit D, Zewinger S, Sarakpi T, Becker E, Hütter G, Wrublewsky S, Küting F, Hohl M, Alansary D, Prates Roma L, Lipp P, Möllmann J, Lehrke M, Laschke MW, Menger MD, Kramann R, Boor P, Jahnen-Dechent W, März W, Böhm M, Laufs U, Niemeyer BA, Fliser D, Ampofo E, Speer T. Schunk SJ, et al. Among authors: fliser d. Circulation. 2021 Sep 14;144(11):893-908. doi: 10.1161/CIRCULATIONAHA.121.053547. Epub 2021 Jul 1. Circulation. 2021. PMID: 34192892 Free article.
Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury.
Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Möllmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, März W, Reiser J, Jankowski J, Fliser D, Speer T, Jankowski V. Schunk SJ, et al. Among authors: fliser d. J Am Soc Nephrol. 2021 Dec 1;32(12):3146-3160. doi: 10.1681/ASN.2021040503. Epub 2021 Dec 1. J Am Soc Nephrol. 2021. PMID: 34588185 Free PMC article.
402 results