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633 results

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Page 1
Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes.
Gottumukkala RV, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA. Gottumukkala RV, et al. Among authors: lee rt. Sci Transl Med. 2012 Jun 13;4(138):138ra80. doi: 10.1126/scitranslmed.3003551. Sci Transl Med. 2012. PMID: 22700956 Free PMC article.
Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy.
Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT. Loffredo FS, et al. Among authors: lee rt. Cell. 2013 May 9;153(4):828-39. doi: 10.1016/j.cell.2013.04.015. Cell. 2013. PMID: 23663781 Free PMC article.
Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.
Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ. Sinha M, et al. Among authors: lee rt. Science. 2014 May 9;344(6184):649-52. doi: 10.1126/science.1251152. Epub 2014 May 5. Science. 2014. PMID: 24797481 Free PMC article.
Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
Poggioli T, Vujic A, Yang P, Macias-Trevino C, Uygur A, Loffredo FS, Pancoast JR, Cho M, Goldstein J, Tandias RM, Gonzalez E, Walker RG, Thompson TB, Wagers AJ, Fong YW, Lee RT. Poggioli T, et al. Among authors: lee rt. Circ Res. 2016 Jan 8;118(1):29-37. doi: 10.1161/CIRCRESAHA.115.307521. Epub 2015 Oct 21. Circ Res. 2016. PMID: 26489925 Free PMC article.
Structural basis for potency differences between GDF8 and GDF11.
Walker RG, Czepnik M, Goebel EJ, McCoy JC, Vujic A, Cho M, Oh J, Aykul S, Walton KL, Schang G, Bernard DJ, Hinck AP, Harrison CA, Martinez-Hackert E, Wagers AJ, Lee RT, Thompson TB. Walker RG, et al. Among authors: lee rt. BMC Biol. 2017 Mar 3;15(1):19. doi: 10.1186/s12915-017-0350-1. BMC Biol. 2017. PMID: 28257634 Free PMC article.
Molecular characterization of latent GDF8 reveals mechanisms of activation.
Walker RG, McCoy JC, Czepnik M, Mills MJ, Hagg A, Walton KL, Cotton TR, Hyvönen M, Lee RT, Gregorevic P, Harrison CA, Thompson TB. Walker RG, et al. Among authors: lee rt. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):E866-E875. doi: 10.1073/pnas.1714622115. Epub 2018 Jan 18. Proc Natl Acad Sci U S A. 2018. PMID: 29348202 Free PMC article.
Analysis of Cre-mediated genetic deletion of Gdf11 in cardiomyocytes of young mice.
Garbern J, Kristl AC, Bassaneze V, Vujic A, Schoemaker H, Sereda R, Peng L, Ricci-Blair EM, Goldstein JM, Walker RG, Bhasin S, Wagers AJ, Lee RT. Garbern J, et al. Among authors: lee rt. Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(1):H201-H212. doi: 10.1152/ajpheart.00615.2018. Epub 2019 May 24. Am J Physiol Heart Circ Physiol. 2019. PMID: 31125255 Free PMC article.
633 results