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MERLIN: a novel BRET-based proximity biosensor for studying mitochondria-ER contact sites.
Hertlein V, Flores-Romero H, Das KK, Fischer S, Heunemann M, Calleja-Felipe M, Knafo S, Hipp K, Harter K, Fitzgerald JC, García-Sáez AJ. Hertlein V, et al. Among authors: fitzgerald jc. Life Sci Alliance. 2019 Dec 9;3(1):e201900600. doi: 10.26508/lsa.201900600. Print 2020 Jan. Life Sci Alliance. 2019. PMID: 31818884 Free PMC article.
Mutations in RHOT1 Disrupt Endoplasmic Reticulum-Mitochondria Contact Sites Interfering with Calcium Homeostasis and Mitochondrial Dynamics in Parkinson's Disease.
Grossmann D, Berenguer-Escuder C, Bellet ME, Scheibner D, Bohler J, Massart F, Rapaport D, Skupin A, Fouquier d'Hérouël A, Sharma M, Ghelfi J, Raković A, Lichtner P, Antony P, Glaab E, May P, Dimmer KS, Fitzgerald JC, Grünewald A, Krüger R. Grossmann D, et al. Among authors: fitzgerald jc. Antioxid Redox Signal. 2019 Dec 1;31(16):1213-1234. doi: 10.1089/ars.2018.7718. Epub 2019 Aug 21. Antioxid Redox Signal. 2019. PMID: 31303019 Free PMC article.
Mitochondrial proteolytic stress induced by loss of mortalin function is rescued by Parkin and PINK1.
Burbulla LF, Fitzgerald JC, Stegen K, Westermeier J, Thost AK, Kato H, Mokranjac D, Sauerwald J, Martins LM, Woitalla D, Rapaport D, Riess O, Proikas-Cezanne T, Rasse TM, Krüger R. Burbulla LF, et al. Among authors: fitzgerald jc. Cell Death Dis. 2014 Apr 17;5(4):e1180. doi: 10.1038/cddis.2014.103. Cell Death Dis. 2014. PMID: 24743735 Free PMC article.
The Therapeutic Potential of Metformin in Neurodegenerative Diseases.
Rotermund C, Machetanz G, Fitzgerald JC. Rotermund C, et al. Among authors: fitzgerald jc. Front Endocrinol (Lausanne). 2018 Jul 19;9:400. doi: 10.3389/fendo.2018.00400. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 30072954 Free PMC article. Review.
Metformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease.
Fitzgerald JC, Zimprich A, Carvajal Berrio DA, Schindler KM, Maurer B, Schulte C, Bus C, Hauser AK, Kübler M, Lewin R, Bobbili DR, Schwarz LM, Vartholomaiou E, Brockmann K, Wüst R, Madlung J, Nordheim A, Riess O, Martins LM, Glaab E, May P, Schenke-Layland K, Picard D, Sharma M, Gasser T, Krüger R. Fitzgerald JC, et al. Brain. 2017 Sep 1;140(9):2444-2459. doi: 10.1093/brain/awx202. Brain. 2017. PMID: 29050400
231 results