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HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR. Wallner M, et al. Among authors: bugger h. Sci Transl Med. 2020 Jan 8;12(525):eaay7205. doi: 10.1126/scitranslmed.aay7205. Sci Transl Med. 2020. PMID: 31915304 Free PMC article.
Impaired SIRT3 activity mediates cardiac dysfunction in endotoxemia by calpain-dependent disruption of ATP synthesis.
Koentges C, Cimolai MC, Pfeil K, Wolf D, Marchini T, Tarkhnishvili A, Hoffmann MM, Odening KE, Diehl P, von Zur Mühlen C, Alvarez S, Bode C, Zirlik A, Bugger H. Koentges C, et al. Among authors: bugger h. J Mol Cell Cardiol. 2019 Aug;133:138-147. doi: 10.1016/j.yjmcc.2019.06.008. Epub 2019 Jun 13. J Mol Cell Cardiol. 2019. PMID: 31201798
Effects of Short Term Adiponectin Receptor Agonism on Cardiac Function and Energetics in Diabetic db/db Mice.
Tarkhnishvili A, Koentges C, Pfeil K, Gollmer J, Byrne NJ, Vosko I, Lueg J, Vogelbacher L, Birkle S, Tang S, Bon-Nawul Mwinyella T, Hoffmann MM, Odening KE, Michel NA, Wolf D, Stachon P, Hilgendorf I, Wallner M, Ljubojevic-Holzer S, von Lewinski D, Rainer P, Sedej S, Sourij H, Bode C, Zirlik A, Bugger H. Tarkhnishvili A, et al. Among authors: bugger h. J Lipid Atheroscler. 2022 May;11(2):161-177. doi: 10.12997/jla.2022.11.2.161. Epub 2022 Mar 31. J Lipid Atheroscler. 2022. PMID: 35656151 Free PMC article.
Dysregulation of the Mitochondrial Proteome Occurs in Mice Lacking Adiponectin Receptor 1.
Pepin ME, Koentges C, Pfeil K, Gollmer J, Kersting S, Wiese S, Hoffmann MM, Odening KE, von Zur Mühlen C, Diehl P, Stachon P, Wolf D, Wende AR, Bode C, Zirlik A, Bugger H. Pepin ME, et al. Among authors: bugger h. Front Endocrinol (Lausanne). 2019 Dec 13;10:872. doi: 10.3389/fendo.2019.00872. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 31920982 Free PMC article.
SIRT3 deficiency impairs mitochondrial and contractile function in the heart.
Koentges C, Pfeil K, Schnick T, Wiese S, Dahlbock R, Cimolai MC, Meyer-Steenbuck M, Cenkerova K, Hoffmann MM, Jaeger C, Odening KE, Kammerer B, Hein L, Bode C, Bugger H. Koentges C, et al. Among authors: bugger h. Basic Res Cardiol. 2015;110(4):36. doi: 10.1007/s00395-015-0493-6. Epub 2015 May 12. Basic Res Cardiol. 2015. PMID: 25962702
89 results