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G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice.
Arbez N, He X, Huang Y, Ren M, Liang Y, Nucifora FC, Wang X, Pei Z, Tessarolo L, Smith WW, Ross CA. Arbez N, et al. Among authors: wang x. Hum Mol Genet. 2020 Mar 13;29(4):580-590. doi: 10.1093/hmg/ddz271. Hum Mol Genet. 2020. PMID: 31813996 Free PMC article.
Cysteamine Protects Neurons from Mutant Huntingtin Toxicity.
Arbez N, Roby E, Akimov S, Eddings C, Ren M, Wang X, Ross CA. Arbez N, et al. Among authors: wang x. J Huntingtons Dis. 2019;8(2):129-143. doi: 10.3233/JHD-180312. J Huntingtons Dis. 2019. PMID: 30856117 Free PMC article.
Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.
Waldron-Roby E, Ratovitski T, Wang X, Jiang M, Watkin E, Arbez N, Graham RK, Hayden MR, Hou Z, Mori S, Swing D, Pletnikov M, Duan W, Tessarollo L, Ross CA. Waldron-Roby E, et al. Among authors: wang x. J Neurosci. 2012 Jan 4;32(1):183-93. doi: 10.1523/JNEUROSCI.1305-11.2012. J Neurosci. 2012. PMID: 22219281 Free PMC article.
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.
Ratovitski T, O'Meally RN, Jiang M, Chaerkady R, Chighladze E, Stewart JC, Wang X, Arbez N, Roby E, Alexandris A, Duan W, Vijayvargia R, Seong IS, Lavery DJ, Cole RN, Ross CA. Ratovitski T, et al. Among authors: wang x. J Proteome Res. 2017 Aug 4;16(8):2692-2708. doi: 10.1021/acs.jproteome.6b00991. Epub 2017 Jul 3. J Proteome Res. 2017. PMID: 28653853 Free PMC article.
Genetic disruption of ankyrin-G in adult mouse forebrain causes cortical synapse alteration and behavior reminiscent of bipolar disorder.
Zhu S, Cordner ZA, Xiong J, Chiu CT, Artola A, Zuo Y, Nelson AD, Kim TY, Zaika N, Woolums BM, Hess EJ, Wang X, Chuang DM, Pletnikov MM, Jenkins PM, Tamashiro KL, Ross CA. Zhu S, et al. Among authors: wang x. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10479-10484. doi: 10.1073/pnas.1700689114. Epub 2017 Sep 11. Proc Natl Acad Sci U S A. 2017. PMID: 28894008 Free PMC article.
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