Ross CA - Search Results

1

G2019S-LRRK2 mutation enhances MPTP-linked Parkinsonism in mice.

Arbez N, He X, Huang Y, Ren M, Liang Y, Nucifora FC, Wang X, Pei Z, Tessarolo L, Smith WW, Ross CA. Arbez N, et al. Among authors: ross ca. Hum Mol Genet. 2020 Mar 13;29(4):580-590. doi: 10.1093/hmg/ddz271. Hum Mol Genet. 2020. PMID: 31813996 Free PMC article.

2

Endoplasmic reticulum stress and mitochondrial cell death pathways mediate A53T mutant alpha-synuclein-induced toxicity.

Smith WW, Jiang H, Pei Z, Tanaka Y, Morita H, Sawa A, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: ross ca. Hum Mol Genet. 2005 Dec 15;14(24):3801-11. doi: 10.1093/hmg/ddi396. Epub 2005 Oct 20. Hum Mol Genet. 2005. PMID: 16239241

3

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.

Smith WW, Pei Z, Jiang H, Moore DJ, Liang Y, West AB, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: ross ca. Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18676-81. doi: 10.1073/pnas.0508052102. Epub 2005 Dec 13. Proc Natl Acad Sci U S A. 2005. PMID: 16352719 Free PMC article.

4

Kinase activity of mutant LRRK2 mediates neuronal toxicity.

Smith WW, Pei Z, Jiang H, Dawson VL, Dawson TM, Ross CA. Smith WW, et al. Among authors: ross ca. Nat Neurosci. 2006 Oct;9(10):1231-3. doi: 10.1038/nn1776. Epub 2006 Sep 17. Nat Neurosci. 2006. PMID: 16980962

5

Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models.

Liu J, Li T, Thomas JM, Pei Z, Jiang H, Engelender S, Ross CA, Smith WW. Liu J, et al. Among authors: ross ca. Hum Mol Genet. 2016 Feb 15;25(4):672-80. doi: 10.1093/hmg/ddv504. Epub 2016 Jan 6. Hum Mol Genet. 2016. PMID: 26744328 Free PMC article.

6

Melatonin attenuates hLRRK2-induced sleep disturbances and synaptic dysfunction in a Drosophila model of Parkinson's disease.

Sun X, Ran D, Zhao X, Huang Y, Long S, Liang F, Guo W, Nucifora FC Jr, Gu H, Lu X, Chen L, Zeng J, Ross CA, Pei Z. Sun X, et al. Among authors: ross ca. Mol Med Rep. 2016 May;13(5):3936-44. doi: 10.3892/mmr.2016.4991. Epub 2016 Mar 16. Mol Med Rep. 2016. PMID: 26985725

7

Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.

Nucifora FC Jr, Nucifora LG, Ng CH, Arbez N, Guo Y, Roby E, Shani V, Engelender S, Wei D, Wang XF, Li T, Moore DJ, Pletnikova O, Troncoso JC, Sawa A, Dawson TM, Smith W, Lim KL, Ross CA. Nucifora FC Jr, et al. Among authors: ross ca. Nat Commun. 2016 Jun 7;7:11792. doi: 10.1038/ncomms11792. Nat Commun. 2016. PMID: 27273569 Free PMC article.

8

GTP-binding inhibitors increase LRRK2-linked ubiquitination and Lewy body-like inclusions.

Thomas JM, Wang X, Guo G, Li T, Dai B, Nucifora LG, Nucifora FC Jr, Liu Z, Xue F, Liu C, Ross CA, Smith WW. Thomas JM, et al. Among authors: ross ca. J Cell Physiol. 2020 Oct;235(10):7309-7320. doi: 10.1002/jcp.29632. Epub 2020 Mar 17. J Cell Physiol. 2020. PMID: 32180220 Free PMC article.

9

Mutant G2019S-LRRK2 Induces Abnormalities in Arteriolar Cerebral Blood Volume in Mouse Brains: An MRI Study.

Ning B, Guo G, Gu C, Xu J, Bibic A, He X, Liu H, Chen L, Wei Z, Duan W, Liu P, Lu H, van Zijl PCM, Ross CA, Smith W, Hua J. Ning B, et al. Among authors: ross ca. Neurodegener Dis. 2020;20(2-3):65-72. doi: 10.1159/000510387. Epub 2020 Nov 5. Neurodegener Dis. 2020. PMID: 33152738 Free PMC article.

10

Mutant VPS35-D620N induces motor dysfunction and impairs DAT-mediated dopamine recycling pathway.

Huang Y, Huang H, Zhou L, Li J, Chen X, Thomas J, He X, Guo W, Zeng Y, Low BC, Liang F, Zeng J, Ross CA, Tan EK, Smith W, Pei Z. Huang Y, et al. Among authors: ross ca. Hum Mol Genet. 2022 Nov 10;31(22):3886-3896. doi: 10.1093/hmg/ddac142. Hum Mol Genet. 2022. PMID: 35766879

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