Morgan BP - Search Results

1

Complement C5 Contributes to Brain Injury After Subarachnoid Hemorrhage.

van Dijk BJ, Meijers JCM, Kloek AT, Knaup VL, Rinkel GJE, Morgan BP, van der Kamp MJ, Osuka K, Aronica E, Ruigrok YM, van de Beek D, Brouwer M, Pekna M, Hol EM, Vergouwen MDI. van Dijk BJ, et al. Among authors: morgan bp. Transl Stroke Res. 2020 Aug;11(4):678-688. doi: 10.1007/s12975-019-00757-0. Epub 2019 Dec 6. Transl Stroke Res. 2020. PMID: 31811640 Free PMC article.

2

Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis.

Woehrl B, Brouwer MC, Murr C, Heckenberg SG, Baas F, Pfister HW, Zwinderman AH, Morgan BP, Barnum SR, van der Ende A, Koedel U, van de Beek D. Woehrl B, et al. Among authors: morgan bp. J Clin Invest. 2011 Oct;121(10):3943-53. doi: 10.1172/JCI57522. Epub 2011 Sep 19. J Clin Invest. 2011. PMID: 21926466 Free PMC article.

3

Adjuvant treatment with dexamethasone plus anti-C5 antibodies improves outcome of experimental pneumococcal meningitis: a randomized controlled trial.

Kasanmoentalib ES, Valls Seron M, Morgan BP, Brouwer MC, van de Beek D. Kasanmoentalib ES, et al. Among authors: morgan bp. J Neuroinflammation. 2015 Aug 15;12:149. doi: 10.1186/s12974-015-0372-y. J Neuroinflammation. 2015. PMID: 26272468 Free PMC article.

4

Alzheimer's disease-associated complement gene variants influence plasma complement protein levels.

Veteleanu A, Stevenson-Hoare J, Keat S, Daskoulidou N, Zetterberg H, Heslegrave A, Escott-Price V, Williams J, Sims R, Zelek WM, Carpanini SM, Morgan BP. Veteleanu A, et al. Among authors: morgan bp. J Neuroinflammation. 2023 Jul 21;20(1):169. doi: 10.1186/s12974-023-02850-6. J Neuroinflammation. 2023. PMID: 37480051 Free PMC article.

5

Absence of the complement regulatory molecule CD59a leads to exacerbated neuropathology after traumatic brain injury in mice.

Stahel PF, Flierl MA, Morgan BP, Persigehl I, Stoll C, Conrad C, Touban BM, Smith WR, Beauchamp K, Schmidt OI, Ertel W, Leinhase I. Stahel PF, et al. Among authors: morgan bp. J Neuroinflammation. 2009 Jan 8;6:2. doi: 10.1186/1742-2094-6-2. J Neuroinflammation. 2009. PMID: 19133139 Free PMC article.

6

Complement-membrane regulatory proteins are absent from the nodes of Ranvier in the peripheral nervous system.

Karbian N, Eshed-Eisenbach Y, Zeibak M, Tabib A, Sukhanov N, Vainshtein A, Morgan BP, Fellig Y, Peles E, Mevorach D. Karbian N, et al. Among authors: morgan bp. J Neuroinflammation. 2023 Oct 24;20(1):245. doi: 10.1186/s12974-023-02920-9. J Neuroinflammation. 2023. PMID: 37875972 Free PMC article.

7

Cardiac myosin inhibitor, CK-586, minimally reduces systolic function and ameliorates obstruction in feline hypertrophic cardiomyopathy.

Rivas VN, Crofton AE, Jauregui CE, Wouters JR, Yang BS, Wittenburg LA, Kaplan JL, Hwee DT, Murphy AN, Morgan BP, Malik FI, Harris SP, Stern JA. Rivas VN, et al. Among authors: morgan bp. Sci Rep. 2024 May 27;14(1):12038. doi: 10.1038/s41598-024-62840-3. Sci Rep. 2024. PMID: 38802475 Free PMC article.

8

Discovery of Nelutroctiv (CK-136), a Selective Cardiac Troponin Activator for the Treatment of Cardiovascular Diseases Associated with Reduced Cardiac Contractility.

Romero A, Ashcraft L, Chandra A, DiMassa V, Cremin P, Collibee SE, Chuang C, Hartman J, Hwee DT, St Jean D, Malinowski J, DeBenedetto M, Moebius D, Payette J, Vargas R, Yeoman J, Motani A, Reagan J, Malik FI, Morgan BP. Romero A, et al. Among authors: morgan bp. J Med Chem. 2024 May 23;67(10):7825-7835. doi: 10.1021/acs.jmedchem.3c02413. Epub 2024 May 10. J Med Chem. 2024. PMID: 38729623 Free PMC article.

9

The complement system in neurodegenerative diseases.

Nimmo J, Byrne RAJ, Daskoulidou N, Watkins LM, Carpanini SM, Zelek WM, Morgan BP. Nimmo J, et al. Among authors: morgan bp. Clin Sci (Lond). 2024 Mar 20;138(6):387-412. doi: 10.1042/CS20230513. Clin Sci (Lond). 2024. PMID: 38505993 Free PMC article.

10

Targeting terminal pathway reduces brain complement activation, amyloid load and synapse loss, and improves cognition in a mouse model of dementia.

Zelek WM, Bevan RJ, Morgan BP. Zelek WM, et al. Among authors: morgan bp. Brain Behav Immun. 2024 May;118:355-363. doi: 10.1016/j.bbi.2024.03.017. Epub 2024 Mar 12. Brain Behav Immun. 2024. PMID: 38485063 Free article.

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