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A no-nonsense approach to hereditary kidney disease.
Pediatr Nephrol. 2020 Nov;35(11):2031-2042. doi: 10.1007/s00467-019-04394-5. Epub 2019 Dec 5.
Pediatr Nephrol. 2020.
PMID: 31807928
Review.
The aminoglycoside geneticin permits translational readthrough of the CTNS W138X nonsense mutation in fibroblasts from patients with nephropathic cystinosis.
Brasell EJ, Chu L, El Kares R, Seo JH, Loesch R, Iglesias DM, Goodyer P.
Brasell EJ, et al.
Pediatr Nephrol. 2019 May;34(5):873-881. doi: 10.1007/s00467-018-4094-0. Epub 2018 Nov 9.
Pediatr Nephrol. 2019.
PMID: 30413946
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The novel aminoglycoside, ELX-02, permits CTNSW138X translational read-through and restores lysosomal cystine efflux in cystinosis.
Brasell EJ, Chu LL, Akpa MM, Eshkar-Oren I, Alroy I, Corsini R, Gilfix BM, Yamanaka Y, Huertas P, Goodyer P.
Brasell EJ, et al.
PLoS One. 2019 Dec 4;14(12):e0223954. doi: 10.1371/journal.pone.0223954. eCollection 2019.
PLoS One. 2019.
PMID: 31800572
Free PMC article.
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Disruption of calcineurin catalytic subunit (cnaA) in Epichloë festucae induces symbiotic defects and intrahyphal hyphae formation.
Mitic M, Berry D, Brasell E, Green K, Young CA, Saikia S, Rakonjac J, Scott B.
Mitic M, et al. Among authors: brasell e.
Mol Plant Pathol. 2018 Jun;19(6):1414-1426. doi: 10.1111/mpp.12624. Epub 2018 Feb 9.
Mol Plant Pathol. 2018.
PMID: 28990722
Free PMC article.
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The Fungal Cell-Wall Integrity MAPK Cascade Is Crucial for Hyphal Network Formation and Maintenance of Restrictive Growth of Epichloë festucae in Symbiosis With Lolium perenne.
Becker Y, Eaton CJ, Brasell E, May KJ, Becker M, Hassing B, Cartwright GM, Reinhold L, Scott B.
Becker Y, et al. Among authors: brasell e.
Mol Plant Microbe Interact. 2015 Jan;28(1):69-85. doi: 10.1094/MPMI-06-14-0183-R.
Mol Plant Microbe Interact. 2015.
PMID: 25303335
Free article.
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