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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction.
Senatorov VV Jr, Friedman AR, Milikovsky DZ, Ofer J, Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ, Moghbel A, Preininger MK, Eddings CR, Harrison HV, Patel R, Shen Y, Ghanim H, Sheng H, Veksler R, Sudmant PH, Becker A, Hart B, Rogawski MA, Dillin A, Friedman A, Kaufer D. Senatorov VV Jr, et al. Among authors: milikovsky dz. Sci Transl Med. 2019 Dec 4;11(521):eaaw8283. doi: 10.1126/scitranslmed.aaw8283. Sci Transl Med. 2019. PMID: 31801886
TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults.
Kim SY, Senatorov VV Jr, Morrissey CS, Lippmann K, Vazquez O, Milikovsky DZ, Gu F, Parada I, Prince DA, Becker AJ, Heinemann U, Friedman A, Kaufer D. Kim SY, et al. Among authors: milikovsky dz. Sci Rep. 2017 Aug 9;7(1):7711. doi: 10.1038/s41598-017-07394-3. Sci Rep. 2017. PMID: 28794441 Free PMC article.
Paroxysmal slow cortical activity in Alzheimer's disease and epilepsy is associated with blood-brain barrier dysfunction.
Milikovsky DZ, Ofer J, Senatorov VV Jr, Friedman AR, Prager O, Sheintuch L, Elazari N, Veksler R, Zelig D, Weissberg I, Bar-Klein G, Swissa E, Hanael E, Ben-Arie G, Schefenbauer O, Kamintsky L, Saar-Ashkenazy R, Shelef I, Shamir MH, Goldberg I, Glik A, Benninger F, Kaufer D, Friedman A. Milikovsky DZ, et al. Sci Transl Med. 2019 Dec 4;11(521):eaaw8954. doi: 10.1126/scitranslmed.aaw8954. Sci Transl Med. 2019. PMID: 31801888
Imaging blood-brain barrier dysfunction in football players.
Weissberg I, Veksler R, Kamintsky L, Saar-Ashkenazy R, Milikovsky DZ, Shelef I, Friedman A. Weissberg I, et al. Among authors: milikovsky dz. JAMA Neurol. 2014 Nov;71(11):1453-5. doi: 10.1001/jamaneurol.2014.2682. JAMA Neurol. 2014. PMID: 25383774 No abstract available.
Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction.
Weissberg I, Wood L, Kamintsky L, Vazquez O, Milikovsky DZ, Alexander A, Oppenheim H, Ardizzone C, Becker A, Frigerio F, Vezzani A, Buckwalter MS, Huguenard JR, Friedman A, Kaufer D. Weissberg I, et al. Among authors: milikovsky dz. Neurobiol Dis. 2015 Jun;78:115-25. doi: 10.1016/j.nbd.2015.02.029. Epub 2015 Mar 30. Neurobiol Dis. 2015. PMID: 25836421 Free PMC article.
Imaging blood-brain barrier dysfunction as a biomarker for epileptogenesis.
Bar-Klein G, Lublinsky S, Kamintsky L, Noyman I, Veksler R, Dalipaj H, Senatorov VV Jr, Swissa E, Rosenbach D, Elazary N, Milikovsky DZ, Milk N, Kassirer M, Rosman Y, Serlin Y, Eisenkraft A, Chassidim Y, Parmet Y, Kaufer D, Friedman A. Bar-Klein G, et al. Among authors: milikovsky dz. Brain. 2017 Jun 1;140(6):1692-1705. doi: 10.1093/brain/awx073. Brain. 2017. PMID: 28444141
Electrocorticographic Dynamics as a Novel Biomarker in Five Models of Epileptogenesis.
Milikovsky DZ, Weissberg I, Kamintsky L, Lippmann K, Schefenbauer O, Frigerio F, Rizzi M, Sheintuch L, Zelig D, Ofer J, Vezzani A, Friedman A. Milikovsky DZ, et al. J Neurosci. 2017 Apr 26;37(17):4450-4461. doi: 10.1523/JNEUROSCI.2446-16.2017. Epub 2017 Mar 22. J Neurosci. 2017. PMID: 28330876 Free PMC article.
Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity.
Bekenstein U, Mishra N, Milikovsky DZ, Hanin G, Zelig D, Sheintuch L, Berson A, Greenberg DS, Friedman A, Soreq H. Bekenstein U, et al. Among authors: milikovsky dz. Proc Natl Acad Sci U S A. 2017 Jun 20;114(25):E4996-E5005. doi: 10.1073/pnas.1701201114. Epub 2017 Jun 5. Proc Natl Acad Sci U S A. 2017. PMID: 28584127 Free PMC article.
15 results