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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction.
Senatorov VV Jr, Friedman AR, Milikovsky DZ, Ofer J, Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ, Moghbel A, Preininger MK, Eddings CR, Harrison HV, Patel R, Shen Y, Ghanim H, Sheng H, Veksler R, Sudmant PH, Becker A, Hart B, Rogawski MA, Dillin A, Friedman A, Kaufer D. Senatorov VV Jr, et al. Among authors: dillin a. Sci Transl Med. 2019 Dec 4;11(521):eaaw8283. doi: 10.1126/scitranslmed.aaw8283. Sci Transl Med. 2019. PMID: 31801886
Can aging be 'drugged'?
Riera CE, Dillin A. Riera CE, et al. Among authors: dillin a. Nat Med. 2015 Dec;21(12):1400-5. doi: 10.1038/nm.4005. Nat Med. 2015. PMID: 26646496 Review.
Reduced IGF-1 signaling delays age-associated proteotoxicity in mice.
Cohen E, Paulsson JF, Blinder P, Burstyn-Cohen T, Du D, Estepa G, Adame A, Pham HM, Holzenberger M, Kelly JW, Masliah E, Dillin A. Cohen E, et al. Among authors: dillin a. Cell. 2009 Dec 11;139(6):1157-69. doi: 10.1016/j.cell.2009.11.014. Cell. 2009. PMID: 20005808 Free PMC article.
Protein homeostasis and aging in neurodegeneration.
Douglas PM, Dillin A. Douglas PM, et al. Among authors: dillin a. J Cell Biol. 2010 Sep 6;190(5):719-29. doi: 10.1083/jcb.201005144. J Cell Biol. 2010. PMID: 20819932 Free PMC article. Review.
Emerging Role of Sensory Perception in Aging and Metabolism.
Riera CE, Dillin A. Riera CE, et al. Among authors: dillin a. Trends Endocrinol Metab. 2016 May;27(5):294-303. doi: 10.1016/j.tem.2016.03.007. Epub 2016 Apr 8. Trends Endocrinol Metab. 2016. PMID: 27067041 Review.
Signaling Networks Determining Life Span.
Riera CE, Merkwirth C, De Magalhaes Filho CD, Dillin A. Riera CE, et al. Among authors: dillin a. Annu Rev Biochem. 2016 Jun 2;85:35-64. doi: 10.1146/annurev-biochem-060815-014451. Annu Rev Biochem. 2016. PMID: 27294438 Review.
A Ribosomal Perspective on Proteostasis and Aging.
Steffen KK, Dillin A. Steffen KK, et al. Among authors: dillin a. Cell Metab. 2016 Jun 14;23(6):1004-1012. doi: 10.1016/j.cmet.2016.05.013. Cell Metab. 2016. PMID: 27304502 Free article. Review.
Mitochondria as Cellular and Organismal Signaling Hubs.
Shen K, Pender CL, Bar-Ziv R, Zhang H, Wickham K, Willey E, Durieux J, Ahmad Q, Dillin A. Shen K, et al. Among authors: dillin a. Annu Rev Cell Dev Biol. 2022 Oct 6;38:179-218. doi: 10.1146/annurev-cellbio-120420-015303. Epub 2022 Jul 8. Annu Rev Cell Dev Biol. 2022. PMID: 35804477 Review.
Aging as an event of proteostasis collapse.
Taylor RC, Dillin A. Taylor RC, et al. Among authors: dillin a. Cold Spring Harb Perspect Biol. 2011 May 1;3(5):a004440. doi: 10.1101/cshperspect.a004440. Cold Spring Harb Perspect Biol. 2011. PMID: 21441594 Free PMC article. Review.
140 results