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Blood-brain barrier dysfunction in aging induces hyperactivation of TGFβ signaling and chronic yet reversible neural dysfunction.
Senatorov VV Jr, Friedman AR, Milikovsky DZ, Ofer J, Saar-Ashkenazy R, Charbash A, Jahan N, Chin G, Mihaly E, Lin JM, Ramsay HJ, Moghbel A, Preininger MK, Eddings CR, Harrison HV, Patel R, Shen Y, Ghanim H, Sheng H, Veksler R, Sudmant PH, Becker A, Hart B, Rogawski MA, Dillin A, Friedman A, Kaufer D. Senatorov VV Jr, et al. Among authors: becker a. Sci Transl Med. 2019 Dec 4;11(521):eaaw8283. doi: 10.1126/scitranslmed.aaw8283. Sci Transl Med. 2019. PMID: 31801886
Albumin storage in neoplastic astroglial elements of gangliogliomas.
Schmitz AK, Grote A, Raabe A, Urbach H, Friedman A, von Lehe M, Becker AJ, Niehusmann P. Schmitz AK, et al. Among authors: becker aj. Seizure. 2013 Mar;22(2):144-50. doi: 10.1016/j.seizure.2012.10.014. Epub 2012 Nov 20. Seizure. 2013. PMID: 23182422 Free PMC article.
Albumin induces excitatory synaptogenesis through astrocytic TGF-β/ALK5 signaling in a model of acquired epilepsy following blood-brain barrier dysfunction.
Weissberg I, Wood L, Kamintsky L, Vazquez O, Milikovsky DZ, Alexander A, Oppenheim H, Ardizzone C, Becker A, Frigerio F, Vezzani A, Buckwalter MS, Huguenard JR, Friedman A, Kaufer D. Weissberg I, et al. Among authors: becker a. Neurobiol Dis. 2015 Jun;78:115-25. doi: 10.1016/j.nbd.2015.02.029. Epub 2015 Mar 30. Neurobiol Dis. 2015. PMID: 25836421 Free PMC article.
TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults.
Kim SY, Senatorov VV Jr, Morrissey CS, Lippmann K, Vazquez O, Milikovsky DZ, Gu F, Parada I, Prince DA, Becker AJ, Heinemann U, Friedman A, Kaufer D. Kim SY, et al. Among authors: becker aj. Sci Rep. 2017 Aug 9;7(1):7711. doi: 10.1038/s41598-017-07394-3. Sci Rep. 2017. PMID: 28794441 Free PMC article.
Evidence for interictal blood-brain barrier dysfunction in people with epilepsy.
Reiter JT, Schulte F, Bauer T, David B, Endler C, Isaak A, Schuch F, Bitzer F, Witt JA, Hattingen E, Deichmann R, Attenberger U, Becker AJ, Helmstaedter C, Radbruch A, Surges R, Friedman A, Rüber T. Reiter JT, et al. Among authors: becker aj. Epilepsia. 2024 May;65(5):1462-1474. doi: 10.1111/epi.17929. Epub 2024 Mar 4. Epilepsia. 2024. PMID: 38436479
Role of CB1 cannabinoid receptors on GABAergic neurons in brain aging.
Albayram O, Alferink J, Pitsch J, Piyanova A, Neitzert K, Poppensieker K, Mauer D, Michel K, Legler A, Becker A, Monory K, Lutz B, Zimmer A, Bilkei-Gorzo A. Albayram O, et al. Among authors: becker a. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11256-61. doi: 10.1073/pnas.1016442108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690345 Free PMC article.
3,997 results