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The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.
Fredriksson R, Sreedharan S, Nordenankar K, Alsiö J, Lindberg FA, Hutchinson A, Eriksson A, Roshanbin S, Ciuculete DM, Klockars A, Todkar A, Hägglund MG, Hellsten SV, Hindlycke V, Västermark Å, Shevchenko G, Olivo G, K C, Kullander K, Moazzami A, Bergquist J, Olszewski PK, Schiöth HB. Fredriksson R, et al. Among authors: olszewski pk. PLoS Genet. 2019 Dec 4;15(12):e1008455. doi: 10.1371/journal.pgen.1008455. eCollection 2019 Dec. PLoS Genet. 2019. PMID: 31800589 Free PMC article.
The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children.
Almén MS, Jacobsson JA, Shaik JH, Olszewski PK, Cedernaes J, Alsiö J, Sreedharan S, Levine AS, Fredriksson R, Marcus C, Schiöth HB. Almén MS, et al. Among authors: olszewski pk. BMC Med Genet. 2010 Apr 9;11:58. doi: 10.1186/1471-2350-11-58. BMC Med Genet. 2010. PMID: 20380707 Free PMC article.
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