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The novel aminoglycoside, ELX-02, permits CTNSW138X translational read-through and restores lysosomal cystine efflux in cystinosis.
PLoS One. 2019 Dec 4;14(12):e0223954. doi: 10.1371/journal.pone.0223954. eCollection 2019.
PLoS One. 2019.
PMID: 31800572
Free PMC article.
Priming the renal progenitor cell.
Iglesias DM, Akpa MM, Goodyer P.
Iglesias DM, et al. Among authors: akpa mm.
Pediatr Nephrol. 2014 Apr;29(4):705-10. doi: 10.1007/s00467-013-2685-3. Epub 2014 Jan 12.
Pediatr Nephrol. 2014.
PMID: 24414605
Review.
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Wilms tumor suppressor, WT1, suppresses epigenetic silencing of the β-catenin gene.
Akpa MM, Iglesias DM, Chu LL, Cybulsky M, Bravi C, Goodyer PR.
Akpa MM, et al.
J Biol Chem. 2015 Jan 23;290(4):2279-88. doi: 10.1074/jbc.M114.573576. Epub 2014 Oct 20.
J Biol Chem. 2015.
PMID: 25331950
Free PMC article.
Item in Clipboard
Wilms Tumor Suppressor, WT1, Cooperates with MicroRNA-26a and MicroRNA-101 to Suppress Translation of the Polycomb Protein, EZH2, in Mesenchymal Stem Cells.
Akpa MM, Iglesias D, Chu L, Thiébaut A, Jentoft I, Hammond L, Torban E, Goodyer PR.
Akpa MM, et al.
J Biol Chem. 2016 Feb 19;291(8):3785-95. doi: 10.1074/jbc.M115.678029. Epub 2015 Dec 10.
J Biol Chem. 2016.
PMID: 26655220
Free PMC article.
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A no-nonsense approach to hereditary kidney disease.
Tokhmafshan F, Dickinson K, Akpa MM, Brasell E, Huertas P, Goodyer PR.
Tokhmafshan F, et al. Among authors: akpa mm.
Pediatr Nephrol. 2020 Nov;35(11):2031-2042. doi: 10.1007/s00467-019-04394-5. Epub 2019 Dec 5.
Pediatr Nephrol. 2020.
PMID: 31807928
Review.
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WT1 regulates expression of DNA repair gene Neil3 during nephrogenesis.
Dickinson K, Hammond L, Akpa M, Chu LL, Lalonde CT, Goumba A, Goodyer P.
Dickinson K, et al.
Am J Physiol Renal Physiol. 2023 Mar 1;324(3):F245-F255. doi: 10.1152/ajprenal.00207.2022. Epub 2022 Dec 22.
Am J Physiol Renal Physiol. 2023.
PMID: 36546838
Free article.
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Inhibition of insulin and T3-induced fatty acid synthase by hexanoate.
Akpa MM, Point F, Sawadogo S, Radenne A, Mounier C.
Akpa MM, et al.
Lipids. 2010 Nov;45(11):997-1009. doi: 10.1007/s11745-010-3465-5. Epub 2010 Sep 1.
Lipids. 2010.
PMID: 20811782
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Hepatic regulation of fatty acid synthase by insulin and T3: evidence for T3 genomic and nongenomic actions.
Radenne A, Akpa M, Martel C, Sawadogo S, Mauvoisin D, Mounier C.
Radenne A, et al.
Am J Physiol Endocrinol Metab. 2008 Oct;295(4):E884-94. doi: 10.1152/ajpendo.90438.2008. Epub 2008 Aug 5.
Am J Physiol Endocrinol Metab. 2008.
PMID: 18682535
Free article.
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