Xin Y - Search Results

1

Filgotinib, a JAK1 Inhibitor, Has No Effect on QT Interval in Healthy Subjects.

Anderson K, Xin Y, Zheng H, Yun C, Kwan E, Qin A, Namour F, Kearney BP, Mathias A. Anderson K, et al. Among authors: xin y. Clin Pharmacol Drug Dev. 2020 Jan;9(1):32-40. doi: 10.1002/cpdd.755. Epub 2019 Dec 2. Clin Pharmacol Drug Dev. 2020. PMID: 31797578 Clinical Trial.

2

Influence of age and renal impairment on the steady state pharmacokinetics of filgotinib, a selective JAK1 inhibitor.

Namour F, Fagard L, Van der Aa A, Harrison P, Xin Y, Tasset C. Namour F, et al. Among authors: xin y. Br J Clin Pharmacol. 2018 Dec;84(12):2779-2789. doi: 10.1111/bcp.13726. Epub 2018 Oct 4. Br J Clin Pharmacol. 2018. PMID: 30088677 Free PMC article.

3

The Relative Bioavailability and Effects of Food and Acid-Reducing Agents on Filgotinib Tablets in Healthy Subjects.

Anderson K, Zheng H, Kotecha M, Cuvin J, Scott B, Sharma S, Qin AR, Namour F, Xin Y. Anderson K, et al. Among authors: xin y. Clin Pharmacol Drug Dev. 2019 Jul;8(5):585-594. doi: 10.1002/cpdd.659. Epub 2019 Feb 15. Clin Pharmacol Drug Dev. 2019. PMID: 30768860 Clinical Trial.

4

Pharmacokinetics and Safety of Momelotinib in Subjects With Hepatic or Renal Impairment.

Xin Y, Kawashima J, Weng W, Kwan E, Tarnowski T, Silverman JA. Xin Y, et al. J Clin Pharmacol. 2018 Apr;58(4):522-532. doi: 10.1002/jcph.1050. Epub 2017 Dec 28. J Clin Pharmacol. 2018. PMID: 29283448 Clinical Trial.

5

Phase 1 First-in-Human, Single- and Multiple-Ascending Dose, and Food Effect Studies to Assess the Safety, Tolerability, and Pharmacokinetics of Presatovir for the Treatment of Respiratory Syncytial Virus Infection.

German P, Xin Y, Chien JW, Weng W, Mackman R, Lewis SA, Meng A, Ling J, Mathias A. German P, et al. Among authors: xin y. J Clin Pharmacol. 2018 Aug;58(8):1025-1034. doi: 10.1002/jcph.1112. Epub 2018 Apr 17. J Clin Pharmacol. 2018. PMID: 29663420

6

The Relative Bioavailability, Food Effect, and Drug Interaction With Omeprazole of Momelotinib Tablet Formulation in Healthy Subjects.

Xin Y, Shao L, Maltzman J, Stefanidis D, Hemenway J, Tarnowski T, Deng W, Silverman JA. Xin Y, et al. Clin Pharmacol Drug Dev. 2018 Mar;7(3):277-286. doi: 10.1002/cpdd.397. Epub 2017 Oct 11. Clin Pharmacol Drug Dev. 2018. PMID: 29024542 Clinical Trial.

7

Phase 1b Study of the Safety, Pharmacokinetics, and Disease-related Outcomes of the Matrix Metalloproteinase-9 Inhibitor Andecaliximab in Patients With Rheumatoid Arthritis.

Gossage DL, Cieslarová B, Ap S, Zheng H, Xin Y, Lal P, Chen G, Smith V, Sundy JS. Gossage DL, et al. Among authors: xin y. Clin Ther. 2018 Jan;40(1):156-165.e5. doi: 10.1016/j.clinthera.2017.11.011. Epub 2017 Dec 26. Clin Ther. 2018. PMID: 29287749 Clinical Trial.

8

Pharmacokinetics and Disposition of Momelotinib Revealed a Disproportionate Human Metabolite-Resolution for Clinical Development.

Zheng J, Xin Y, Zhang J, Subramanian R, Murray BP, Whitney JA, Warr MR, Ling J, Moorehead L, Kwan E, Hemenway J, Smith BJ, Silverman JA. Zheng J, et al. Among authors: xin y. Drug Metab Dispos. 2018 Mar;46(3):237-247. doi: 10.1124/dmd.117.078899. Epub 2018 Jan 8. Drug Metab Dispos. 2018. PMID: 29311136

9

Population pharmacokinetic analysis from phase I and phase II studies of the humanized monovalent antibody, onartuzumab (MetMAb), in patients with advanced solid tumors.

Xin Y, Jin D, Eppler S, Damico-Beyer LA, Joshi A, Davis JD, Kaur S, Nijem I, Bothos J, Peterson A, Patel P, Bai S. Xin Y, et al. J Clin Pharmacol. 2013 Nov;53(11):1103-11. doi: 10.1002/jcph.148. Epub 2013 Aug 7. J Clin Pharmacol. 2013. PMID: 23922054 Clinical Trial.

10

The Drug-Drug Interaction Profile of Presatovir.

Xin Y, Weng W, Murray BP, Eisenberg EJ, Chien JW, Ling J, Silverman JA. Xin Y, et al. J Clin Pharmacol. 2018 Jun;58(6):771-780. doi: 10.1002/jcph.1073. Epub 2018 Feb 7. J Clin Pharmacol. 2018. PMID: 29412463 Clinical Trial.

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