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Page 1
Global redox proteome and phosphoproteome analysis reveals redox switch in Akt.
Su Z, Burchfield JG, Yang P, Humphrey SJ, Yang G, Francis D, Yasmin S, Shin SY, Norris DM, Kearney AL, Astore MA, Scavuzzo J, Fisher-Wellman KH, Wang QP, Parker BL, Neely GG, Vafaee F, Chiu J, Yeo R, Hogg PJ, Fazakerley DJ, Nguyen LK, Kuyucak S, James DE. Su Z, et al. Among authors: astore ma. Nat Commun. 2019 Dec 2;10(1):5486. doi: 10.1038/s41467-019-13114-4. Nat Commun. 2019. PMID: 31792197 Free PMC article.
Mitochondrial electron transport chain, ceramide and Coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle.
Diaz-Vegas A, Madsen S, Cooke KC, Carroll L, Khor JXY, Turner N, Lim XY, Astore MA, Morris J, Don A, Garfield A, Zarini S, Zemski Berry KA, Ryan A, Bergman BC, Brozinick JT, James DE, Burchfield JG. Diaz-Vegas A, et al. Among authors: astore ma. bioRxiv [Preprint]. 2023 Sep 19:2023.03.10.532020. doi: 10.1101/2023.03.10.532020. bioRxiv. 2023. PMID: 36945619 Free PMC article. Updated. Preprint.
Mitochondrial electron transport chain, ceramide, and coenzyme Q are linked in a pathway that drives insulin resistance in skeletal muscle.
Diaz-Vegas A, Madsen S, Cooke KC, Carroll L, Khor JXY, Turner N, Lim XY, Astore MA, Morris JC, Don AS, Garfield A, Zarini S, Zemski Berry KA, Ryan AP, Bergman BC, Brozinick JT, James DE, Burchfield JG. Diaz-Vegas A, et al. Among authors: astore ma. Elife. 2023 Dec 27;12:RP87340. doi: 10.7554/eLife.87340. Elife. 2023. PMID: 38149844 Free PMC article.
Q1291H-CFTR molecular dynamics simulations and ex vivo theratyping in nasal epithelial models and clinical response to elexacaftor/tezacaftor/ivacaftor in a Q1291H/F508del patient.
Allan KM, Astore MA, Kardia E, Wong SL, Fawcett LK, Bell JL, Visser S, Chen PC, Griffith R, Jaffe A, Sivam S, Vittorio O, Kuyucak S, Waters SA. Allan KM, et al. Among authors: astore ma. Front Mol Biosci. 2023 Jun 1;10:1148501. doi: 10.3389/fmolb.2023.1148501. eCollection 2023. Front Mol Biosci. 2023. PMID: 37325471 Free PMC article.
Molecular dynamics and functional characterization of I37R-CFTR lasso mutation provide insights into channel gating activity.
Wong SL, Awatade NT, Astore MA, Allan KM, Carnell MJ, Slapetova I, Chen PC, Capraro A, Fawcett LK, Whan RM, Griffith R, Ooi CY, Kuyucak S, Jaffe A, Waters SA. Wong SL, et al. Among authors: astore ma. iScience. 2021 Dec 31;25(1):103710. doi: 10.1016/j.isci.2021.103710. eCollection 2022 Jan 21. iScience. 2021. PMID: 35072004 Free PMC article.
Molecular Dynamics and Theratyping in Airway and Gut Organoids Reveal R352Q-CFTR Conductance Defect.
Wong SL, Awatade NT, Astore MA, Allan KM, Carnell MJ, Slapetova I, Chen PC, Setiadi J, Pandzic E, Fawcett LK, Widger JR, Whan RM, Griffith R, Ooi CY, Kuyucak S, Jaffe A, Waters SA. Wong SL, et al. Among authors: astore ma. Am J Respir Cell Mol Biol. 2022 Jul;67(1):99-111. doi: 10.1165/rcmb.2021-0337OC. Am J Respir Cell Mol Biol. 2022. PMID: 35471184 Free PMC article.
Protein dynamics underlying allosteric regulation.
Astore MA, Pradhan AS, Thiede EH, Hanson SM. Astore MA, et al. Curr Opin Struct Biol. 2024 Feb;84:102768. doi: 10.1016/j.sbi.2023.102768. Epub 2024 Jan 11. Curr Opin Struct Biol. 2024. PMID: 38215528 Free article. Review.