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A Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), UCM-05194, Shows Efficacy in Neuropathic Pain Amelioration.
González-Gil I, Zian D, Vázquez-Villa H, Hernández-Torres G, Martínez RF, Khiar-Fernández N, Rivera R, Kihara Y, Devesa I, Mathivanan S, Del Valle CR, Zambrana-Infantes E, Puigdomenech M, Cincilla G, Sanchez-Martinez M, Rodríguez de Fonseca F, Ferrer-Montiel AV, Chun J, López-Vales R, López-Rodríguez ML, Ortega-Gutiérrez S. González-Gil I, et al. Among authors: rivera r. J Med Chem. 2020 Mar 12;63(5):2372-2390. doi: 10.1021/acs.jmedchem.9b01287. Epub 2019 Dec 16. J Med Chem. 2020. PMID: 31790581 Free PMC article.
Biological effects of lysophospholipids.
Rivera R, Chun J. Rivera R, et al. Rev Physiol Biochem Pharmacol. 2008;160:25-46. doi: 10.1007/112_0507. Rev Physiol Biochem Pharmacol. 2008. PMID: 18481029 Review.
Lysophosphatidic acid signaling may initiate fetal hydrocephalus.
Yung YC, Mutoh T, Lin ME, Noguchi K, Rivera RR, Choi JW, Kingsbury MA, Chun J. Yung YC, et al. Among authors: rivera rr. Sci Transl Med. 2011 Sep 7;3(99):99ra87. doi: 10.1126/scitranslmed.3002095. Sci Transl Med. 2011. PMID: 21900594 Free PMC article.
870 results