Griffith DC - Search Results

1

Challenges in the bioanalysis of tetracyclines: Epimerisation and chelation with metals.

Bayliss MAJ, Rigdova K, Kyriakides M, Grier S, Lovering AM, Ellery K, Griffith DC, MacGowan A. Bayliss MAJ, et al. Among authors: griffith dc. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Dec 15;1134-1135:121807. doi: 10.1016/j.jchromb.2019.121807. Epub 2019 Oct 4. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 31783250

2

Development, validation and application of a novel HPLC-MS/MS method for the measurement of minocycline in human plasma and urine.

Bayliss MAJ, Rigdova K, Kyriakides M, Grier S, Lovering AM, Williams H, Griffith DC, MacGowan A. Bayliss MAJ, et al. Among authors: griffith dc. J Pharm Biomed Anal. 2019 May 30;169:90-98. doi: 10.1016/j.jpba.2019.02.036. Epub 2019 Feb 26. J Pharm Biomed Anal. 2019. PMID: 30844627 Free article.

3

Pharmacodynamics of Minocycline against Acinetobacter baumannii in a Rat Pneumonia Model.

Tarazi Z, Sabet M, Dudley MN, Griffith DC. Tarazi Z, et al. Among authors: griffith dc. Antimicrob Agents Chemother. 2019 Jan 29;63(2):e01671-18. doi: 10.1128/AAC.01671-18. Print 2019 Feb. Antimicrob Agents Chemother. 2019. PMID: 30397059 Free PMC article.

4

In Vivo Activity of QPX7728, an Ultrabroad-Spectrum Beta-Lactamase Inhibitor, in Combination with Beta-Lactams against Carbapenem-Resistant Klebsiella pneumoniae.

Sabet M, Tarazi Z, Griffith DC. Sabet M, et al. Among authors: griffith dc. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01267-20. doi: 10.1128/AAC.01267-20. Print 2020 Oct 20. Antimicrob Agents Chemother. 2020. PMID: 32839224 Free PMC article.

5

QPX7728, An Ultra-Broad-Spectrum B-Lactamase Inhibitor for Intravenous and Oral Therapy: Overview of Biochemical and Microbiological Characteristics.

Lomovskaya O, Tsivkovski R, Sun D, Reddy R, Totrov M, Hecker S, Griffith D, Loutit J, Dudley M. Lomovskaya O, et al. Front Microbiol. 2021 Jul 5;12:697180. doi: 10.3389/fmicb.2021.697180. eCollection 2021. Front Microbiol. 2021. PMID: 34290688 Free PMC article. Review.

6

A Phase 1 Study of the Safety, Tolerability, and Pharmacokinetics of Biapenem in Healthy Adult Subjects.

Griffith DC, Morgan EE, Dudley MN, Loutit JS. Griffith DC, et al. Antimicrob Agents Chemother. 2023 May 1;65(5):e02612-20. doi: 10.1128/AAC.02612-20. Epub 2021 Mar 8. Antimicrob Agents Chemother. 2023. PMID: 33685898 Free PMC article.

7

Pharmacodynamics of Meropenem against Acinetobacter baumannii in a Neutropenic Mouse Thigh Infection Model.

Sabet M, Tarazi Z, Griffith DC. Sabet M, et al. Among authors: griffith dc. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02388-19. doi: 10.1128/AAC.02388-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31988101 Free PMC article.

8

Discovery of Cyclic Boronic Acid QPX7728, an Ultrabroad-Spectrum Inhibitor of Serine and Metallo-β-lactamases.

Hecker SJ, Reddy KR, Lomovskaya O, Griffith DC, Rubio-Aparicio D, Nelson K, Tsivkovski R, Sun D, Sabet M, Tarazi Z, Parkinson J, Totrov M, Boyer SH, Glinka TW, Pemberton OA, Chen Y, Dudley MN. Hecker SJ, et al. Among authors: griffith dc. J Med Chem. 2020 Jul 23;63(14):7491-7507. doi: 10.1021/acs.jmedchem.9b01976. Epub 2020 Apr 2. J Med Chem. 2020. PMID: 32150407

9

Discovery of a Cyclic Boronic Acid β-Lactamase Inhibitor (RPX7009) with Utility vs Class A Serine Carbapenemases.

Hecker SJ, Reddy KR, Totrov M, Hirst GC, Lomovskaya O, Griffith DC, King P, Tsivkovski R, Sun D, Sabet M, Tarazi Z, Clifton MC, Atkins K, Raymond A, Potts KT, Abendroth J, Boyer SH, Loutit JS, Morgan EE, Durso S, Dudley MN. Hecker SJ, et al. Among authors: griffith dc. J Med Chem. 2015 May 14;58(9):3682-92. doi: 10.1021/acs.jmedchem.5b00127. Epub 2015 Mar 17. J Med Chem. 2015. PMID: 25782055

10

Vaborbactam: Spectrum of Beta-Lactamase Inhibition and Impact of Resistance Mechanisms on Activity in Enterobacteriaceae.

Lomovskaya O, Sun D, Rubio-Aparicio D, Nelson K, Tsivkovski R, Griffith DC, Dudley MN. Lomovskaya O, et al. Among authors: griffith dc. Antimicrob Agents Chemother. 2017 Oct 24;61(11):e01443-17. doi: 10.1128/AAC.01443-17. Print 2017 Nov. Antimicrob Agents Chemother. 2017. PMID: 28848018 Free PMC article.

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