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Nuclear poly(A)-binding protein aggregates misplace a pre-mRNA outside of SC35 speckle causing its abnormal splicing.
Klein P, Oloko M, Roth F, Montel V, Malerba A, Jarmin S, Gidaro T, Popplewell L, Perie S, Lacau St Guily J, de la Grange P, Antoniou MN, Dickson G, Butler-Browne G, Bastide B, Mouly V, Trollet C. Klein P, et al. Among authors: de la grange p. Nucleic Acids Res. 2016 Dec 15;44(22):10929-10945. doi: 10.1093/nar/gkw703. Epub 2016 Aug 9. Nucleic Acids Res. 2016. PMID: 27507886 Free PMC article.
Modifying macrophages at the periphery has the capacity to change microglial reactivity and to extend ALS survival.
Chiot A, Zaïdi S, Iltis C, Ribon M, Berriat F, Schiaffino L, Jolly A, de la Grange P, Mallat M, Bohl D, Millecamps S, Seilhean D, Lobsiger CS, Boillée S. Chiot A, et al. Among authors: de la grange p. Nat Neurosci. 2020 Nov;23(11):1339-1351. doi: 10.1038/s41593-020-00718-z. Epub 2020 Oct 19. Nat Neurosci. 2020. PMID: 33077946 Free article.
Splicing factor and exon profiling across human tissues.
de la Grange P, Gratadou L, Delord M, Dutertre M, Auboeuf D. de la Grange P, et al. Nucleic Acids Res. 2010 May;38(9):2825-38. doi: 10.1093/nar/gkq008. Epub 2010 Jan 27. Nucleic Acids Res. 2010. PMID: 20110256 Free PMC article.
101 results