Tice CM - Search Results

1

Tight-Binding Hydroxypyrazole HIV-1 Nef Inhibitors Suppress Viral Replication in Donor Mononuclear Cells and Reverse Nef-Mediated MHC-I Downregulation.

Shi H, Tice CM, Emert-Sedlak L, Chen L, Li WF, Carlsen M, Wrobel JE, Reitz AB, Smithgall TE. Shi H, et al. Among authors: tice cm. ACS Infect Dis. 2020 Feb 14;6(2):302-312. doi: 10.1021/acsinfecdis.9b00382. Epub 2019 Dec 16. ACS Infect Dis. 2020. PMID: 31775511 Free PMC article.

2

Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.

Emert-Sedlak LA, Shi H, Tice CM, Chen L, Alvarado JJ, Shu ST, Du S, Thomas CE, Wrobel JE, Reitz AB, Smithgall TE. Emert-Sedlak LA, et al. Among authors: tice cm. Viruses. 2022 Sep 13;14(9):2025. doi: 10.3390/v14092025. Viruses. 2022. PMID: 36146831 Free PMC article. Review.

3

Discovery of Potent Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1 Using a Novel Growth-Based Protocol of in Silico Screening and Optimization in CONTOUR.

Liu Z, Singh SB, Zheng Y, Lindblom P, Tice C, Dong C, Zhuang L, Zhao Y, Kruk BA, Lala D, Claremon DA, McGeehan GM, Gregg RD, Cain R. Liu Z, et al. J Chem Inf Model. 2019 Aug 26;59(8):3422-3436. doi: 10.1021/acs.jcim.9b00198. Epub 2019 Aug 8. J Chem Inf Model. 2019. PMID: 31355641

4

The utilization of spirocyclic scaffolds in novel drug discovery.

Zheng YJ, Tice CM. Zheng YJ, et al. Among authors: tice cm. Expert Opin Drug Discov. 2016 Sep;11(9):831-4. doi: 10.1080/17460441.2016.1195367. Epub 2016 Jun 9. Expert Opin Drug Discov. 2016. PMID: 27233084 No abstract available.

5

Discovery of VTP-27999, an Alkyl Amine Renin Inhibitor with Potential for Clinical Utility.

Jia L, Simpson RD, Yuan J, Xu Z, Zhao W, Cacatian S, Tice CM, Guo J, Ishchenko A, Singh SB, Wu Z, McKeever BM, Bukhtiyarov Y, Johnson JA, Doe CP, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA. Jia L, et al. Among authors: tice cm. ACS Med Chem Lett. 2011 Aug 9;2(10):747-51. doi: 10.1021/ml200137x. eCollection 2011 Oct 13. ACS Med Chem Lett. 2011. PMID: 24900262 Free PMC article.

6

Structure based design of 11β-HSD1 inhibitors.

Singh S, Tice C. Singh S, et al. Curr Pharm Biotechnol. 2010 Nov;11(7):779-91. doi: 10.2174/138920110792927748. Curr Pharm Biotechnol. 2010. PMID: 20809895 Review.

7

Discovery and optimization of adamantyl carbamate inhibitors of 11β-HSD1.

Tice CM, Zhao W, Krosky PM, Kruk BA, Berbaum J, Johnson JA, Bukhtiyarov Y, Panemangalore R, Scott BB, Zhao Y, Bruno JG, Howard L, Togias J, Ye YJ, Singh SB, McKeever BM, Lindblom PR, Guo J, Guo R, Nar H, Schuler-Metz A, Gregg RE, Leftheris K, Harrison RK, McGeehan GM, Zhuang L, Claremon DA. Tice CM, et al. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6725-9. doi: 10.1016/j.bmcl.2010.08.142. Epub 2010 Sep 7. Bioorg Med Chem Lett. 2010. PMID: 20864344

8

Structure-based design and synthesis of 1,3-oxazinan-2-one inhibitors of 11β-hydroxysteroid dehydrogenase type 1.

Xu Z, Tice CM, Zhao W, Cacatian S, Ye YJ, Singh SB, Lindblom P, McKeever BM, Krosky PM, Kruk BA, Berbaum J, Harrison RK, Johnson JA, Bukhtiyarov Y, Panemangalore R, Scott BB, Zhao Y, Bruno JG, Togias J, Guo J, Guo R, Carroll PJ, McGeehan GM, Zhuang L, He W, Claremon DA. Xu Z, et al. Among authors: tice cm. J Med Chem. 2011 Sep 8;54(17):6050-62. doi: 10.1021/jm2005354. Epub 2011 Aug 4. J Med Chem. 2011. PMID: 21786805

9

Discovery of BI 135585, an in vivo efficacious oxazinanone-based 11β hydroxysteroid dehydrogenase type 1 inhibitor.

Zhuang L, Tice CM, Xu Z, Zhao W, Cacatian S, Ye YJ, Singh SB, Lindblom P, McKeever BM, Krosky PM, Zhao Y, Lala D, Kruk BA, Meng S, Howard L, Johnson JA, Bukhtiyarov Y, Panemangalore R, Guo J, Guo R, Himmelsbach F, Hamilton B, Schuler-Metz A, Schauerte H, Gregg R, McGeehan GM, Leftheris K, Claremon DA. Zhuang L, et al. Among authors: tice cm. Bioorg Med Chem. 2017 Jul 15;25(14):3649-3657. doi: 10.1016/j.bmc.2017.04.033. Epub 2017 Apr 29. Bioorg Med Chem. 2017. PMID: 28528082

10

Design and optimization of renin inhibitors: Orally bioavailable alkyl amines.

Tice CM, Xu Z, Yuan J, Simpson RD, Cacatian ST, Flaherty PT, Zhao W, Guo J, Ishchenko A, Singh SB, Wu Z, Scott BB, Bukhtiyarov Y, Berbaum J, Mason J, Panemangalore R, Cappiello MG, Müller D, Harrison RK, McGeehan GM, Dillard LW, Baldwin JJ, Claremon DA. Tice CM, et al. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3541-5. doi: 10.1016/j.bmcl.2009.04.140. Epub 2009 May 5. Bioorg Med Chem Lett. 2009. PMID: 19457666

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