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Synthesis and evaluation of orally active small molecule HIV-1 Nef antagonists.
Emert-Sedlak LA, Loughran HM, Shi H, Kulp JL 3rd, Shu ST, Zhao J, Day BW, Wrobel JE, Reitz AB, Smithgall TE. Emert-Sedlak LA, et al. Among authors: reitz ab. Bioorg Med Chem Lett. 2016 Mar 1;26(5):1480-1484. doi: 10.1016/j.bmcl.2016.01.043. Epub 2016 Jan 21. Bioorg Med Chem Lett. 2016. PMID: 26852364 Free PMC article.
Antiretroviral Drug Discovery Targeting the HIV-1 Nef Virulence Factor.
Emert-Sedlak LA, Shi H, Tice CM, Chen L, Alvarado JJ, Shu ST, Du S, Thomas CE, Wrobel JE, Reitz AB, Smithgall TE. Emert-Sedlak LA, et al. Among authors: reitz ab. Viruses. 2022 Sep 13;14(9):2025. doi: 10.3390/v14092025. Viruses. 2022. PMID: 36146831 Free PMC article. Review.
Dipeptide Prodrugs of the Glutamate Modulator Riluzole.
Pelletier JC, Chen S, Bian H, Shah R, Smith GR, Wrobel JE, Reitz AB. Pelletier JC, et al. Among authors: reitz ab. ACS Med Chem Lett. 2018 Jun 15;9(7):752-756. doi: 10.1021/acsmedchemlett.8b00189. eCollection 2018 Jul 12. ACS Med Chem Lett. 2018. PMID: 30034613 Free PMC article.
Quinoxaline-based inhibitors of Ebola and Marburg VP40 egress.
Loughran HM, Han Z, Wrobel JE, Decker SE, Ruthel G, Freedman BD, Harty RN, Reitz AB. Loughran HM, et al. Among authors: reitz ab. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3429-35. doi: 10.1016/j.bmcl.2016.06.053. Epub 2016 Jun 23. Bioorg Med Chem Lett. 2016. PMID: 27377328 Free PMC article.
Acinetobacter baumannii OxPhos inhibitors as selective anti-infective agents.
Rubin H, Selwood T, Yano T, Weaver DG, Loughran HM, Costanzo MJ, Scott RW, Wrobel JE, Freeman KB, Reitz AB. Rubin H, et al. Among authors: reitz ab. Bioorg Med Chem Lett. 2015 Jan 15;25(2):378-83. doi: 10.1016/j.bmcl.2014.11.020. Epub 2014 Nov 22. Bioorg Med Chem Lett. 2015. PMID: 25496770
A Method for C2 Acylation of 1,3-Indandiones.
Larsen BJ, Rosano RJ, Ford-Hutchinson TA, Reitz AB, Wrobel JE. Larsen BJ, et al. Among authors: reitz ab. Tetrahedron. 2018 May 31;74(22):2762-2768. doi: 10.1016/j.tet.2018.04.041. Epub 2018 Apr 17. Tetrahedron. 2018. PMID: 29760536 Free PMC article.
Compound FC-10696 Inhibits Egress of Marburg Virus.
Han Z, Ye H, Liang J, Shepley-McTaggart A, Wrobel JE, Reitz AB, Whigham A, Kavelish KN, Saporito MS, Freedman BD, Shtanko O, Harty RN. Han Z, et al. Among authors: reitz ab. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0008621. doi: 10.1128/AAC.00086-21. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33846137 Free PMC article.
144 results