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Synthesis of novel 4-Boc-piperidone chalcones and evaluation of their cytotoxic activity against highly-metastatic cancer cells.
Ocasio-Malavé C, Donate MJ, Sánchez MM, Sosa-Rivera JM, Mooney JW, Pereles-De León TA, Carballeira NM, Zayas B, Vélez-Gerena CE, Martínez-Ferrer M, Sanabria-Ríos DJ. Ocasio-Malavé C, et al. Among authors: carballeira nm. Bioorg Med Chem Lett. 2020 Jan 1;30(1):126760. doi: 10.1016/j.bmcl.2019.126760. Epub 2019 Oct 28. Bioorg Med Chem Lett. 2020. PMID: 31767266 Free PMC article.
Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity.
Sanabria-Ríos DJ, Rivera-Torres Y, Rosario J, Ríos C, Gutierrez R, Carballeira NM, Vélez C, Zayas B, Álvarez-Colón F, Ortiz-Soto G, Serrano V, Altieri-Rivera J, Ríos-Olivares E, Rodríguez JW. Sanabria-Ríos DJ, et al. Among authors: carballeira nm. Bioorg Med Chem Lett. 2015;25(10):2174-80. doi: 10.1016/j.bmcl.2015.03.065. Epub 2015 Mar 31. Bioorg Med Chem Lett. 2015. PMID: 25881826 Free PMC article.
Chemical conjugation of 2-hexadecynoic acid to C5-curcumin enhances its antibacterial activity against multi-drug resistant bacteria.
Sanabria-Ríos DJ, Rivera-Torres Y, Rosario J, Gutierrez R, Torres-García Y, Montano N, Ortíz-Soto G, Ríos-Olivares E, Rodríguez JW, Carballeira NM. Sanabria-Ríos DJ, et al. Among authors: carballeira nm. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5067-71. doi: 10.1016/j.bmcl.2015.10.022. Epub 2015 Oct 14. Bioorg Med Chem Lett. 2015. PMID: 26483137 Free PMC article.
Antibacterial fatty acids: An update of possible mechanisms of action and implications in the development of the next-generation of antibacterial agents.
Casillas-Vargas G, Ocasio-Malavé C, Medina S, Morales-Guzmán C, Del Valle RG, Carballeira NM, Sanabria-Ríos DJ. Casillas-Vargas G, et al. Among authors: carballeira nm. Prog Lipid Res. 2021 Apr;82:101093. doi: 10.1016/j.plipres.2021.101093. Epub 2021 Feb 9. Prog Lipid Res. 2021. PMID: 33577909 Free PMC article. Review.
Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation.
García-Cazorla Y, Getino M, Sanabria-Ríos DJ, Carballeira NM, de la Cruz F, Arechaga I, Cabezón E. García-Cazorla Y, et al. Among authors: carballeira nm. J Biol Chem. 2018 Oct 26;293(43):16923-16930. doi: 10.1074/jbc.RA118.004716. Epub 2018 Sep 10. J Biol Chem. 2018. PMID: 30201608 Free PMC article.
Antibacterial activity of 2-alkynoic fatty acids against multidrug-resistant bacteria.
Sanabria-Ríos DJ, Rivera-Torres Y, Maldonado-Domínguez G, Domínguez I, Ríos C, Díaz D, Rodríguez JW, Altieri-Rivera JS, Ríos-Olivares E, Cintrón G, Montano N, Carballeira NM. Sanabria-Ríos DJ, et al. Among authors: carballeira nm. Chem Phys Lipids. 2014 Feb;178:84-91. doi: 10.1016/j.chemphyslip.2013.12.006. Epub 2013 Dec 21. Chem Phys Lipids. 2014. PMID: 24365283 Free PMC article.
104 results