Umezawa K - Search Results

1

The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation.

Fu H, Alabdullah M, Großmann J, Spieler F, Abdosh R, Lutz V, Kalies K, Knöpp K, Rieckmann M, Koch S, Noutsias M, Pilowski C, Dutzmann J, Sedding D, Hüttelmaier S, Umezawa K, Werdan K, Loppnow H. Fu H, et al. Among authors: umezawa k. Cell Death Dis. 2019 Nov 21;10(12):880. doi: 10.1038/s41419-019-2109-9. Cell Death Dis. 2019. PMID: 31754207 Free PMC article.

2

Dehydroxymethylepoxyquinomicin suppresses atopic dermatitis-like lesions in a stratum corneum-removed murine model through NF-κB inhibition.

Jiang X, He H, Xie Z, Wen H, Li X, Li X, Ma J, Umezawa K, Zhang Y. Jiang X, et al. Among authors: umezawa k. Immunopharmacol Immunotoxicol. 2019 Feb;41(1):32-39. doi: 10.1080/08923973.2018.1510962. Epub 2019 Feb 6. Immunopharmacol Immunotoxicol. 2019. PMID: 30724631

3

Screening of new bioactive metabolites for diabetes therapy.

Sidthipong K, Todo S, Takei I, Kojima I, Umezawa K. Sidthipong K, et al. Among authors: umezawa k. Intern Emerg Med. 2013 Apr;8 Suppl 1:S57-9. doi: 10.1007/s11739-013-0922-1. Intern Emerg Med. 2013. PMID: 23504230 Review.

4

Anti-Inflammatory Effect of Dehydroxymethylepoxyquinomicin, a Nuclear factor-κB Inhibitor, on Endotoxin-Induced Uveitis in Rats In vivo and In vitro.

Ando Y, Keino H, Kudo A, Hirakata A, Okada AA, Umezawa K. Ando Y, et al. Among authors: umezawa k. Ocul Immunol Inflamm. 2020;28(2):240-248. doi: 10.1080/09273948.2019.1568502. Epub 2019 Apr 5. Ocul Immunol Inflamm. 2020. PMID: 30950670

5

Anti‑inflammatory effects of the NF‑κB inhibitor dehydroxymethylepoxyquinomicin on ARPE‑19 cells.

Ando Y, Sato Y, Kudo A, Watanabe T, Hirakata A, Okada AA, Umezawa K, Keino H. Ando Y, et al. Among authors: umezawa k. Mol Med Rep. 2020 Jul;22(1):582-590. doi: 10.3892/mmr.2020.11115. Epub 2020 May 4. Mol Med Rep. 2020. PMID: 32377746

6

Inhibition of RANKL- and LPS-induced osteoclast differentiations by novel NF-κB inhibitor DTCM-glutarimide.

Koide N, Kaneda A, Yokochi T, Umezawa K. Koide N, et al. Among authors: umezawa k. Int Immunopharmacol. 2015 Mar;25(1):162-8. doi: 10.1016/j.intimp.2015.01.004. Epub 2015 Jan 21. Int Immunopharmacol. 2015. PMID: 25617668

7

Anti-inflammatory effects of novel AP-1 and NF-κB inhibitors in dextran-sulfate-sodium-induced colitis in rats.

El-Salhy M, Umezawa K. El-Salhy M, et al. Among authors: umezawa k. Int J Mol Med. 2016 Jun;37(6):1457-64. doi: 10.3892/ijmm.2016.2560. Epub 2016 Apr 12. Int J Mol Med. 2016. PMID: 27082818 Free PMC article.

8

Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response.

Burgess JT, Bolderson E, Adams MN, Baird AM, Zhang SD, Gately KA, Umezawa K, O'Byrne KJ, Richard DJ. Burgess JT, et al. Among authors: umezawa k. Cell Death Dis. 2016 Nov 10;7(11):e2469. doi: 10.1038/cddis.2016.364. Cell Death Dis. 2016. PMID: 27831555 Free PMC article.

9

Inhibition of MMP-2-mediated cellular invasion by NF-κB inhibitor DHMEQ in 3D culture of breast carcinoma MDA-MB-231 cells: A model for early phase of metastasis.

Ukaji T, Lin Y, Okada S, Umezawa K. Ukaji T, et al. Among authors: umezawa k. Biochem Biophys Res Commun. 2017 Mar 25;485(1):76-81. doi: 10.1016/j.bbrc.2017.02.022. Epub 2017 Feb 8. Biochem Biophys Res Commun. 2017. PMID: 28188787

10

Therapeutic activity of plant-derived alkaloid conophylline on metabolic syndrome and neurodegenerative disease models.

Umezawa K, Kojima I, Simizu S, Lin Y, Fukatsu H, Koide N, Nakade Y, Yoneda M. Umezawa K, et al. Hum Cell. 2018 Apr;31(2):95-101. doi: 10.1007/s13577-017-0196-4. Epub 2017 Dec 16. Hum Cell. 2018. PMID: 29249016 Review.

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