Sawa M - Search Results

1

Rafii MS, Kleschevnikov AM, Sawa M, Mobley WC. Rafii MS, et al. Among authors: sawa m. Handb Clin Neurol. 2019;167:321-336. doi: 10.1016/B978-0-12-804766-8.00017-0. Handb Clin Neurol. 2019. PMID: 31753140 Review.

2

Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration.

Xu W, Weissmiller AM, White JA 2nd, Fang F, Wang X, Wu Y, Pearn ML, Zhao X, Sawa M, Chen S, Gunawardena S, Ding J, Mobley WC, Wu C. Xu W, et al. Among authors: sawa m. J Clin Invest. 2016 May 2;126(5):1815-33. doi: 10.1172/JCI82409. Epub 2016 Apr 11. J Clin Invest. 2016. PMID: 27064279 Free PMC article.

3

Dysregulation of neurotrophin signaling in the pathogenesis of Alzheimer disease and of Alzheimer disease in Down syndrome.

Chen XQ, Sawa M, Mobley WC. Chen XQ, et al. Among authors: sawa m. Free Radic Biol Med. 2018 Jan;114:52-61. doi: 10.1016/j.freeradbiomed.2017.10.341. Epub 2017 Oct 12. Free Radic Biol Med. 2018. PMID: 29031834 Free PMC article. Review.

4

Preclinical validation of a potent γ-secretase modulator for Alzheimer's disease prevention.

Rynearson KD, Ponnusamy M, Prikhodko O, Xie Y, Zhang C, Nguyen P, Hug B, Sawa M, Becker A, Spencer B, Florio J, Mante M, Salehi B, Arias C, Galasko D, Head BP, Johnson G, Lin JH, Duddy SK, Rissman RA, Mobley WC, Thinakaran G, Tanzi RE, Wagner SL. Rynearson KD, et al. Among authors: sawa m. J Exp Med. 2021 Apr 5;218(4):e20202560. doi: 10.1084/jem.20202560. J Exp Med. 2021. PMID: 33651103 Free PMC article.

5

Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model.

Sawa M, Overk C, Becker A, Derse D, Albay R, Weldy K, Salehi A, Beach TG, Doran E, Head E, Yu YE, Mobley WC. Sawa M, et al. Alzheimers Dement. 2022 Jun;18(6):1203-1234. doi: 10.1002/alz.12463. Epub 2021 Nov 10. Alzheimers Dement. 2022. PMID: 34757693 Free PMC article.

6

Retromer Proteins Reduced in Down Syndrome and the Dp16 Model: Impact of APP Dose and Preclinical Studies of a γ-Secretase Modulator.

Chen XQ, Sawa M, Becker A, Karachentsev D, Zuo X, Rynearson KD, Tanzi RE, Mobley WC. Chen XQ, et al. Among authors: sawa m. Ann Neurol. 2023 Aug;94(2):245-258. doi: 10.1002/ana.26659. Epub 2023 Apr 29. Ann Neurol. 2023. PMID: 37042072

7

Identification of small molecule activators of cryptochrome.

Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T, Welsh DK, Brenner DA, Doyle FJ 3rd, Schultz PG, Kay SA. Hirota T, et al. Among authors: sawa m. Science. 2012 Aug 31;337(6098):1094-7. doi: 10.1126/science.1223710. Epub 2012 Jul 12. Science. 2012. PMID: 22798407 Free PMC article.

8

Multi-level Modulation of Light Signaling by GIGANTEA Regulates Both the Output and Pace of the Circadian Clock.

Nohales MA, Liu W, Duffy T, Nozue K, Sawa M, Pruneda-Paz JL, Maloof JN, Jacobsen SE, Kay SA. Nohales MA, et al. Among authors: sawa m. Dev Cell. 2019 Jun 17;49(6):840-851.e8. doi: 10.1016/j.devcel.2019.04.030. Epub 2019 May 16. Dev Cell. 2019. PMID: 31105011 Free PMC article.

9

GIGANTEA directly activates Flowering Locus T in Arabidopsis thaliana.

Sawa M, Kay SA. Sawa M, et al. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11698-703. doi: 10.1073/pnas.1106771108. Epub 2011 Jun 27. Proc Natl Acad Sci U S A. 2011. PMID: 21709243 Free PMC article.

10

FKF1 and GIGANTEA complex formation is required for day-length measurement in Arabidopsis.

Sawa M, Nusinow DA, Kay SA, Imaizumi T. Sawa M, et al. Science. 2007 Oct 12;318(5848):261-5. doi: 10.1126/science.1146994. Epub 2007 Sep 13. Science. 2007. PMID: 17872410 Free PMC article.

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