Natarajan A - Search Results

1

Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective.

Ahmed A, Boulton S, Shao H, Akimoto M, Natarajan A, Cheng X, Melacini G. Ahmed A, et al. Among authors: natarajan a. Cells. 2019 Nov 19;8(11):1462. doi: 10.3390/cells8111462. Cells. 2019. PMID: 31752286 Free PMC article. Review.

2

Structure-Activity Relationship Studies with Tetrahydroquinoline Analogs as EPAC Inhibitors.

Sonawane YA, Zhu Y, Garrison JC, Ezell EL, Zahid M, Cheng X, Natarajan A. Sonawane YA, et al. Among authors: natarajan a. ACS Med Chem Lett. 2017 Oct 2;8(11):1183-1187. doi: 10.1021/acsmedchemlett.7b00358. eCollection 2017 Nov 9. ACS Med Chem Lett. 2017. PMID: 29375750 Free PMC article.

3

Recent Advances in Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein.

Abid M, Sonawane YA, Contreras JI, Rana S, Natarajan A. Abid M, et al. Among authors: natarajan a. Curr Med Chem. 2017;24(40):4488-4514. doi: 10.2174/0929867324666170912092659. Curr Med Chem. 2017. PMID: 28901269 Review.

4

PROTACs in Ovarian Cancer: Current Advancements and Future Perspectives.

Vorderbruggen M, Velázquez-Martínez CA, Natarajan A, Karpf AR. Vorderbruggen M, et al. Among authors: natarajan a. Int J Mol Sci. 2024 May 7;25(10):5067. doi: 10.3390/ijms25105067. Int J Mol Sci. 2024. PMID: 38791105 Free PMC article. Review.

5

Cyclin Dependent Kinase 9 Inhibitors for Cancer Therapy.

Sonawane YA, Taylor MA, Napoleon JV, Rana S, Contreras JI, Natarajan A. Sonawane YA, et al. Among authors: natarajan a. J Med Chem. 2016 Oct 13;59(19):8667-8684. doi: 10.1021/acs.jmedchem.6b00150. Epub 2016 Jun 3. J Med Chem. 2016. PMID: 27171036 Free PMC article.

6

Characterization of Promiscuous Binding of Phosphor Ligands to Breast-Cancer-Gene 1 (BRCA1) C-Terminal (BRCT): Molecular Dynamics, Free Energy, Entropy and Inhibitor Design.

You W, Huang YM, Kizhake S, Natarajan A, Chang CE. You W, et al. Among authors: natarajan a. PLoS Comput Biol. 2016 Aug 25;12(8):e1005057. doi: 10.1371/journal.pcbi.1005057. eCollection 2016 Aug. PLoS Comput Biol. 2016. PMID: 27560145 Free PMC article.

7

Symbiotic prodrugs (SymProDs) dual targeting of NFkappaB and CDK.

Rana S, Kour S, Sonawane YA, Robb CM, Contreras JI, Kizhake S, Zahid M, Karpf AR, Natarajan A. Rana S, et al. Among authors: natarajan a. Chem Biol Drug Des. 2020 Aug;96(2):773-784. doi: 10.1111/cbdd.13684. Epub 2020 Apr 22. Chem Biol Drug Des. 2020. PMID: 32237047 Free PMC article.

8

Small molecule binding to inhibitor of nuclear factor kappa-B kinase subunit beta in an ATP non-competitive manner.

Napoleon JV, Singh S, Rana S, Bendjennat M, Kumar V, Kizhake S, Palermo NY, Ouellette MM, Huxford T, Natarajan A. Napoleon JV, et al. Among authors: natarajan a. Chem Commun (Camb). 2021 May 11;57(38):4678-4681. doi: 10.1039/d1cc01245b. Chem Commun (Camb). 2021. PMID: 33977973 Free PMC article.

9

High-throughput fluorescence polarization assay to identify inhibitors of Cbl(TKB)-protein tyrosine kinase interactions.

Kumar EA, Charvet CD, Lokesh GL, Natarajan A. Kumar EA, et al. Among authors: natarajan a. Anal Biochem. 2011 Apr 15;411(2):254-60. doi: 10.1016/j.ab.2010.11.038. Epub 2010 Dec 1. Anal Biochem. 2011. PMID: 21129358 Free PMC article.

10

Beyond the frog: the evolution of homology models of human IKKβ.

Palermo NY, Natarajan A. Palermo NY, et al. Among authors: natarajan a. Bioorg Med Chem Lett. 2011 Oct 15;21(20):6081-4. doi: 10.1016/j.bmcl.2011.08.051. Epub 2011 Aug 19. Bioorg Med Chem Lett. 2011. PMID: 21911292 Free PMC article.

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