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HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms.
Yue L, Sharma V, Horvat NP, Akuffo AA, Beatty MS, Murdun C, Colin C, Billington JMR, Goodheart WE, Sahakian E, Zhang L, Powers JJ, Amin NE, Lambert-Showers QT, Darville LN, Pinilla-Ibarz J, Reuther GW, Wright KL, Conti C, Lee JY, Zheng X, Ng PY, Martin MW, Marshall CG, Koomen JM, Levine RL, Verma A, Grimes HL, Sotomayor EM, Shao Z, Epling-Burnette PK. Yue L, et al. Among authors: sotomayor em. Blood. 2020 Jan 16;135(3):191-207. doi: 10.1182/blood.2019895326. Blood. 2020. PMID: 31750881 Free PMC article.
Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia.
Maharaj K, Powers JJ, Achille A, Deng S, Fonseca R, Pabon-Saldana M, Quayle SN, Jones SS, Villagra A, Sotomayor EM, Sahakian E, Pinilla-Ibarz J. Maharaj K, et al. Among authors: sotomayor em. Blood Adv. 2018 Nov 13;2(21):3012-3024. doi: 10.1182/bloodadvances.2018020065. Blood Adv. 2018. PMID: 30425065 Free PMC article.
T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model.
Woods DM, Woan KV, Cheng F, Sodré AL, Wang D, Wu Y, Wang Z, Chen J, Powers J, Pinilla-Ibarz J, Yu Y, Zhang Y, Wu X, Zheng X, Weber J, Hancock WW, Seto E, Villagra A, Yu XZ, Sotomayor EM. Woods DM, et al. Among authors: sotomayor em. Blood. 2017 Jul 13;130(2):146-155. doi: 10.1182/blood-2016-08-731505. Epub 2017 May 26. Blood. 2017. PMID: 28550044 Free PMC article.
Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology.
Sahakian E, Chen J, Powers JJ, Chen X, Maharaj K, Deng SL, Achille AN, Lienlaf M, Wang HW, Cheng F, Sodré AL, Distler A, Xing L, Perez-Villarroel P, Wei S, Villagra A, Seto E, Sotomayor EM, Horna P, Pinilla-Ibarz J. Sahakian E, et al. Among authors: sotomayor em. J Leukoc Biol. 2017 Aug;102(2):475-486. doi: 10.1189/jlb.1A0415-176RRR. Epub 2017 May 26. J Leukoc Biol. 2017. PMID: 28550123 Free PMC article.
Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma.
Mostofa A, Distler A, Meads MB, Sahakian E, Powers JJ, Achille A, Noyes D, Wright G, Fang B, Izumi V, Koomen J, Rampakrishnan R, Nguyen TP, De Avila G, Silva AS, Sudalagunta P, Canevarolo RR, Siqueira Silva MDC, Alugubelli RR, Dai HA, Kulkarni A, Dalton WS, Hampton OA, Welsh EA, Teer JK, Tungesvik A, Wright KL, Pinilla-Ibarz J, Sotomayor EM, Shain KH, Brayer J. Mostofa A, et al. Among authors: sotomayor em. JCI Insight. 2021 Dec 22;6(24):e151713. doi: 10.1172/jci.insight.151713. JCI Insight. 2021. PMID: 34793338 Free PMC article.
137 results