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Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease.
Nucleic Acids Res. 2020 Jan 10;48(1):36-54. doi: 10.1093/nar/gkz976.
Nucleic Acids Res. 2020.
PMID: 31745548
Free PMC article.
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease.
Southwell AL, Kordasiewicz HB, Langbehn D, Skotte NH, Parsons MP, Villanueva EB, Caron NS, Østergaard ME, Anderson LM, Xie Y, Cengio LD, Findlay-Black H, Doty CN, Fitsimmons B, Swayze EE, Seth PP, Raymond LA, Frank Bennett C, Hayden MR.
Southwell AL, et al. Among authors: cengio ld.
Sci Transl Med. 2018 Oct 3;10(461):eaar3959. doi: 10.1126/scitranslmed.aar3959.
Sci Transl Med. 2018.
PMID: 30282695
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Corrigendum to "Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease" [Neurobiology of Disease, 2024 Jan:190:106376].
Bartl S, Xie Y, Potluri N, Kesineni R, Hencak K, Cengio LD, Balazs K, Oueslati A, Parth M, Salhat N, Siddu A, Smrzka O, Cicchetti F, Staffler G, Hayden MR, Southwell AL.
Bartl S, et al. Among authors: cengio ld.
Neurobiol Dis. 2024 Apr;193:106444. doi: 10.1016/j.nbd.2024.106444. Epub 2024 Feb 24.
Neurobiol Dis. 2024.
PMID: 38402018
Free article.
No abstract available.
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Reducing huntingtin by immunotherapy delays disease progression in a mouse model of Huntington disease.
Bartl S, Xie Y, Potluri N, Kesineni R, Hencak K, Cengio LD, Balazs K, Oueslati A, Parth M, Salhat N, Siddu A, Smrzka O, Cicchetti F, Straffler G, Hayden MR, Southwell AL.
Bartl S, et al. Among authors: cengio ld.
Neurobiol Dis. 2024 Jan;190:106376. doi: 10.1016/j.nbd.2023.106376. Epub 2023 Dec 12.
Neurobiol Dis. 2024.
PMID: 38092268
Free article.
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