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PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host-microbe intersection during SIV infection.
Crakes KR, Santos Rocha C, Grishina I, Hirao LA, Napoli E, Gaulke CA, Fenton A, Datta S, Arredondo J, Marco ML, Sankaran-Walters S, Cortopassi G, Giulivi C, Dandekar S. Crakes KR, et al. Among authors: hirao la. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24819-24829. doi: 10.1073/pnas.1908977116. Epub 2019 Nov 18. Proc Natl Acad Sci U S A. 2019. PMID: 31740620 Free PMC article.
Early mucosal sensing of SIV infection by paneth cells induces IL-1β production and initiates gut epithelial disruption.
Hirao LA, Grishina I, Bourry O, Hu WK, Somrit M, Sankaran-Walters S, Gaulke CA, Fenton AN, Li JA, Crawford RW, Chuang F, Tarara R, Marco ML, Bäumler AJ, Cheng H, Dandekar S. Hirao LA, et al. PLoS Pathog. 2014 Aug 28;10(8):e1004311. doi: 10.1371/journal.ppat.1004311. eCollection 2014 Aug. PLoS Pathog. 2014. PMID: 25166758 Free PMC article.
Th17 cells and regulatory T cells in elite control over HIV and SIV.
Hartigan-O'Connor DJ, Hirao LA, McCune JM, Dandekar S. Hartigan-O'Connor DJ, et al. Among authors: hirao la. Curr Opin HIV AIDS. 2011 May;6(3):221-7. doi: 10.1097/COH.0b013e32834577b3. Curr Opin HIV AIDS. 2011. PMID: 21399494 Free PMC article. Review.
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