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Wnt family member 4 (WNT4) and WNT3A activate cell-autonomous Wnt signaling independent of porcupine O-acyltransferase or Wnt secretion.
J Biol Chem. 2019 Dec 27;294(52):19950-19966. doi: 10.1074/jbc.RA119.009615. Epub 2019 Nov 18.
J Biol Chem. 2019.
PMID: 31740580
Free PMC article.
Estrogen Regulation of mTOR Signaling and Mitochondrial Function in Invasive Lobular Carcinoma Cell Lines Requires WNT4.
Shackleford MT, Rao DM, Bordeaux EK, Hicks HM, Towers CG, Sottnik JL, Oesterreich S, Sikora MJ.
Shackleford MT, et al.
Cancers (Basel). 2020 Oct 12;12(10):2931. doi: 10.3390/cancers12102931.
Cancers (Basel). 2020.
PMID: 33053661
Free PMC article.
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WNT4 Regulates Cellular Metabolism via Intracellular Activity at the Mitochondria in Breast and Gynecologic Cancers.
Sottnik JL, Shackleford MT, Robinson SK, Villagomez FR, Bahnassy S, Oesterreich S, Hu J, Madak-Erdogan Z, Riggins RB, Corr BR, Cook LS, Treviño LS, Bitler BG, Sikora MJ.
Sottnik JL, et al. Among authors: shackleford mt.
Cancer Res Commun. 2024 Jan 17;4(1):134-151. doi: 10.1158/2767-9764.CRC-23-0275.
Cancer Res Commun. 2024.
PMID: 38112643
Free PMC article.
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