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Page 1
Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability.
Gimmelli R, Persico M, Imperatore C, Saccoccia F, Guidi A, Casertano M, Luciano P, Pietrantoni A, Bertuccini L, Paladino A, Papoff G, Menna M, Fattorusso C, Ruberti G. Gimmelli R, et al. Among authors: persico m. ACS Infect Dis. 2020 Jan 10;6(1):124-137. doi: 10.1021/acsinfecdis.9b00252. Epub 2019 Nov 27. ACS Infect Dis. 2020. PMID: 31718145
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G. Fattorusso C, et al. Among authors: persico m. J Med Chem. 2005 Nov 17;48(23):7153-65. doi: 10.1021/jm050257d. J Med Chem. 2005. PMID: 16279773
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
Gemma S, Kukreja G, Fattorusso C, Persico M, Romano MP, Altarelli M, Savini L, Campiani G, Fattorusso E, Basilico N, Taramelli D, Yardley V, Butini S. Gemma S, et al. Among authors: persico m. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5384-8. doi: 10.1016/j.bmcl.2006.07.060. Epub 2006 Aug 4. Bioorg Med Chem Lett. 2006. PMID: 16890433
Insight into the mechanism of action of plakortins, simple 1,2-dioxane antimalarials.
Taglialatela-Scafati O, Fattorusso E, Romano A, Scala F, Barone V, Cimino P, Stendardo E, Catalanotti B, Persico M, Fattorusso C. Taglialatela-Scafati O, et al. Among authors: persico m. Org Biomol Chem. 2010 Feb 21;8(4):846-56. doi: 10.1039/b918600j. Epub 2009 Dec 16. Org Biomol Chem. 2010. PMID: 20135043
A new class of antimalarial dioxanes obtained through a simple two-step synthetic approach: rational design and structure-activity relationship studies.
Persico M, Quintavalla A, Rondinelli F, Trombini C, Lombardo M, Fattorusso C, Azzarito V, Taramelli D, Parapini S, Corbett Y, Chianese G, Fattorusso E, Taglialatela-Scafati O. Persico M, et al. J Med Chem. 2011 Dec 22;54(24):8526-40. doi: 10.1021/jm201056j. Epub 2011 Nov 23. J Med Chem. 2011. PMID: 22054038
Investigating the role of T7 and T12 residues on the biological properties of thrombin-binding aptamer: enhancement of anticoagulant activity by a single nucleobase modification.
Borbone N, Bucci M, Oliviero G, Morelli E, Amato J, D'Atri V, D'Errico S, Vellecco V, Cirino G, Piccialli G, Fattorusso C, Varra M, Mayol L, Persico M, Scuotto M. Borbone N, et al. Among authors: persico m. J Med Chem. 2012 Dec 13;55(23):10716-28. doi: 10.1021/jm301414f. Epub 2012 Nov 19. J Med Chem. 2012. PMID: 23126678
505 results