Houston D - Search Results

1

Insights into the Effects of Cancer Associated Mutations at the UPF2 and ATP-Binding Sites of NMD Master Regulator: UPF1.

Kalathiya U, Padariya M, Pawlicka K, Verma CS, Houston D, Hupp TR, Alfaro JA. Kalathiya U, et al. Among authors: houston d. Int J Mol Sci. 2019 Nov 11;20(22):5644. doi: 10.3390/ijms20225644. Int J Mol Sci. 2019. PMID: 31718065 Free PMC article.

2

Discovery of a novel ligand that modulates the protein-protein interactions of the AAA+ superfamily oncoprotein reptin.

Healy AR, Houston DR, Remnant L, Huart AS, Brychtova V, Maslon MM, Meers O, Muller P, Krejci A, Blackburn EA, Vojtesek B, Hernychova L, Walkinshaw MD, Westwood NJ, Hupp TR. Healy AR, et al. Among authors: houston dr. Chem Sci. 2015 May 1;6(5):3109-3116. doi: 10.1039/c4sc03885a. Epub 2015 Mar 20. Chem Sci. 2015. PMID: 28706685 Free PMC article.

3

Mono-Substituted Hydrocarbon Diastereomer Combinations Reveal Stapled Peptides with High Structural Fidelity.

McWhinnie FS, Sepp K, Wilson C, Kunath T, Hupp TR, Baker TS, Houston DR, Hulme AN. McWhinnie FS, et al. Chemistry. 2018 Feb 9;24(9):2094-2097. doi: 10.1002/chem.201705983. Epub 2018 Jan 19. Chemistry. 2018. PMID: 29267987

4

An inter-subunit protein-peptide interface that stabilizes the specific activity and oligomerization of the AAA+ chaperone Reptin.

Coufalova D, Remnant L, Hernychova L, Muller P, Healy A, Kannan S, Westwood N, Verma CS, Vojtesek B, Hupp TR, Houston DR. Coufalova D, et al. Among authors: houston dr. J Proteomics. 2019 May 15;199:89-101. doi: 10.1016/j.jprot.2019.02.012. Epub 2019 Mar 9. J Proteomics. 2019. PMID: 30862565

5

Recognition Dynamics of Cancer Mutations on the ERp57-Tapasin Interface.

Padariya M, Kalathiya U, Houston DR, Alfaro JA. Padariya M, et al. Cancers (Basel). 2020 Mar 20;12(3):737. doi: 10.3390/cancers12030737. Cancers (Basel). 2020. PMID: 32244998 Free PMC article.

6

Comparison of ATP-binding pockets and discovery of homologous recombination inhibitors.

Blay V, Gailiunaite S, Lee CY, Chang HY, Hupp T, Houston DR, Chi P. Blay V, et al. Bioorg Med Chem. 2022 Sep 15;70:116923. doi: 10.1016/j.bmc.2022.116923. Epub 2022 Jul 9. Bioorg Med Chem. 2022. PMID: 35841829 Free article.

7

Fatty-acylation target sequence in the ligand-binding domain of vertebrate steroid receptors demarcates evolution from estrogen-related receptors.

Lathe R, Houston DR. Lathe R, et al. J Steroid Biochem Mol Biol. 2018 Nov;184:20-28. doi: 10.1016/j.jsbmb.2018.07.010. Epub 2018 Jul 17. J Steroid Biochem Mol Biol. 2018. PMID: 30026064 Free article.

8

PRL3-DDX21 Transcriptional Control of Endolysosomal Genes Restricts Melanocyte Stem Cell Differentiation.

Johansson JA, Marie KL, Lu Y, Brombin A, Santoriello C, Zeng Z, Zich J, Gautier P, von Kriegsheim A, Brunsdon H, Wheeler AP, Dreger M, Houston DR, Dooley CM, Sims AH, Busch-Nentwich EM, Zon LI, Illingworth RS, Patton EE. Johansson JA, et al. Dev Cell. 2020 Aug 10;54(3):317-332.e9. doi: 10.1016/j.devcel.2020.06.013. Epub 2020 Jul 10. Dev Cell. 2020. PMID: 32652076 Free PMC article.

9

Evidence that nuclear receptors are related to terpene synthases.

Houston DR, Hanna JG, Lathe JC, Hillier SG, Lathe R. Houston DR, et al. J Mol Endocrinol. 2022 Mar 14;68(3):153-166. doi: 10.1530/JME-21-0156. J Mol Endocrinol. 2022. PMID: 35112668 Free PMC article.

10

Structure-based exploration of cyclic dipeptide chitinase inhibitors.

Houston DR, Synstad B, Eijsink VG, Stark MJ, Eggleston IM, van Aalten DM. Houston DR, et al. J Med Chem. 2004 Nov 4;47(23):5713-20. doi: 10.1021/jm049940a. J Med Chem. 2004. PMID: 15509170 Free article.

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