Varela J - Search Results

1

New aryloxy-quinone derivatives with promising activity on Trypanosoma cruzi.

Espinosa-Bustos C, Vázquez K, Varela J, Cerecetto H, Paulino M, Segura R, Pizarro J, Vera B, González M, Zarate AM, Salas CO. Espinosa-Bustos C, et al. Among authors: varela j. Arch Pharm (Weinheim). 2020 Jan;353(1):e1900213. doi: 10.1002/ardp.201900213. Epub 2019 Nov 11. Arch Pharm (Weinheim). 2020. PMID: 31709599

2

Identification of novel benzimidazole derivatives as anti-Trypanosoma cruzi agents: solid-phase synthesis, structure-activity relationships and molecular docking studies.

Ríos N, Varela J, Birriel E, González M, Cerecetto H, Merlino A, Porcal W. Ríos N, et al. Among authors: varela j. Future Med Chem. 2013 Oct;5(15):1719-32. doi: 10.4155/fmc.13.160. Future Med Chem. 2013. PMID: 24144409

3

Synthesis and biological characterization of new aryloxyindole-4,9-diones as potent trypanosomicidal agents.

Tapia RA, Salas CO, Vázquez K, Espinosa-Bustos C, Soto-Delgado J, Varela J, Birriel E, Cerecetto H, González M, Paulino M. Tapia RA, et al. Among authors: varela j. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3919-22. doi: 10.1016/j.bmcl.2014.06.044. Epub 2014 Jun 24. Bioorg Med Chem Lett. 2014. PMID: 25008454

4

Massive screening yields novel and selective Trypanosoma cruzi triosephosphate isomerase dimer-interface-irreversible inhibitors with anti-trypanosomal activity.

Alvarez G, Aguirre-López B, Varela J, Cabrera M, Merlino A, López GV, Lavaggi ML, Porcal W, Di Maio R, González M, Cerecetto H, Cabrera N, Pérez-Montfort R, de Gómez-Puyou MT, Gómez-Puyou A. Alvarez G, et al. Among authors: varela j. Eur J Med Chem. 2010 Dec;45(12):5767-72. doi: 10.1016/j.ejmech.2010.09.034. Epub 2010 Sep 19. Eur J Med Chem. 2010. PMID: 20889239

5

Activity on Trypanosoma cruzi, erythrocytes lysis and biologically relevant physicochemical properties of Pd(II) and Pt(II) complexes of thiosemicarbazones derived from 1-indanones.

Santos D, Parajón-Costa B, Rossi M, Caruso F, Benítez D, Varela J, Cerecetto H, González M, Gómez N, Caputto ME, Moglioni AG, Moltrasio GY, Finkielsztein LM, Gambino D. Santos D, et al. Among authors: varela j. J Inorg Biochem. 2012 Dec;117:270-6. doi: 10.1016/j.jinorgbio.2012.08.024. Epub 2012 Sep 24. J Inorg Biochem. 2012. PMID: 23063173

6

Bioactive-guided identification of labdane diterpenoids from aerial parts of Aristeguietia glutinosa as anti-Trypanosoma cruzi agents.

Varela J, Lavaggi ML, Cabrera M, Rodríguez A, Miño P, Chiriboga X, Cerecetto H, González M. Varela J, et al. Nat Prod Commun. 2012 Sep;7(9):1139-42. Nat Prod Commun. 2012. PMID: 23074890

7

New oxidovanadium(IV) N-acylhydrazone complexes: promising antileishmanial and antitrypanosomal agents.

Benítez J, Cavalcanti de Queiroz A, Correia I, Alves MA, Alexandre-Moreira MS, Barreiro EJ, Lima LM, Varela J, González M, Cerecetto H, Moreno V, Pessoa JC, Gambino D. Benítez J, et al. Among authors: varela j. Eur J Med Chem. 2013 Apr;62:20-7. doi: 10.1016/j.ejmech.2012.12.036. Epub 2012 Dec 29. Eur J Med Chem. 2013. PMID: 23353731

8

A new series of heteroleptic oxidovanadium(IV) compounds with phenanthroline-derived co-ligands: selective Trypanosoma cruzi growth inhibitors.

Fernández M, Varela J, Correia I, Birriel E, Castiglioni J, Moreno V, Costa Pessoa J, Cerecetto H, González M, Gambino D. Fernández M, et al. Among authors: varela j. Dalton Trans. 2013 Sep 7;42(33):11900-11. doi: 10.1039/c3dt50512j. Dalton Trans. 2013. PMID: 23787783

9

Optimization of antitrypanosomatid agents: identification of nonmutagenic drug candidates with in vivo activity.

Álvarez G, Varela J, Márquez P, Gabay M, Arias Rivas CE, Cuchilla K, Echeverría GA, Piro OE, Chorilli M, Leal SM, Escobar P, Serna E, Torres S, Yaluff G, Vera de Bilbao NI, González M, Cerecetto H. Álvarez G, et al. Among authors: varela j. J Med Chem. 2014 May 22;57(10):3984-99. doi: 10.1021/jm500018m. Epub 2014 May 2. J Med Chem. 2014. PMID: 24749923

10

In vivo anti-Trypanosoma cruzi activity of hydro-ethanolic extract and isolated active principles from Aristeguietia glutinosa and mechanism of action studies.

Varela J, Serna E, Torres S, Yaluff G, de Bilbao NI, Miño P, Chiriboga X, Cerecetto H, González M. Varela J, et al. Molecules. 2014 Jun 23;19(6):8488-502. doi: 10.3390/molecules19068488. Molecules. 2014. PMID: 24959677 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

998 results

Search Page