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Epigenetic mechanisms underlying the therapeutic effects of HDAC inhibitors in chronic myeloid leukemia.
Biochem Pharmacol. 2020 Mar;173:113698. doi: 10.1016/j.bcp.2019.113698. Epub 2019 Nov 7.
Biochem Pharmacol. 2020.
PMID: 31706847
Review.
Anti-cancer effects of naturally derived compounds targeting histone deacetylase 6-related pathways.
Lernoux M, Schnekenburger M, Dicato M, Diederich M.
Lernoux M, et al.
Pharmacol Res. 2018 Mar;129:337-356. doi: 10.1016/j.phrs.2017.11.004. Epub 2017 Nov 11.
Pharmacol Res. 2018.
PMID: 29133216
Review.
Item in Clipboard
Novel HDAC inhibitor MAKV-8 and imatinib synergistically kill chronic myeloid leukemia cells via inhibition of BCR-ABL/MYC-signaling: effect on imatinib resistance and stem cells.
Lernoux M, Schnekenburger M, Losson H, Vermeulen K, Hahn H, Gérard D, Lee JY, Mazumder A, Ahamed M, Christov C, Kim DW, Dicato M, Bormans G, Han BW, Diederich M.
Lernoux M, et al.
Clin Epigenetics. 2020 May 19;12(1):69. doi: 10.1186/s13148-020-00839-z.
Clin Epigenetics. 2020.
PMID: 32430012
Free PMC article.
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The HDAC6 inhibitor 7b induces BCR-ABL ubiquitination and downregulation and synergizes with imatinib to trigger apoptosis in chronic myeloid leukemia.
Losson H, Gajulapalli SR, Lernoux M, Lee JY, Mazumder A, Gérard D, Seidel C, Hahn H, Christov C, Dicato M, Kirsch G, Han BW, Schnekenburger M, Diederich M.
Losson H, et al. Among authors: lernoux m.
Pharmacol Res. 2020 Oct;160:105058. doi: 10.1016/j.phrs.2020.105058. Epub 2020 Jun 30.
Pharmacol Res. 2020.
PMID: 32619722
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Susceptibility of multiple myeloma to B-cell lymphoma 2 family inhibitors.
Lernoux M, Schnekenburger M, Dicato M, Diederich M.
Lernoux M, et al.
Biochem Pharmacol. 2021 Jun;188:114526. doi: 10.1016/j.bcp.2021.114526. Epub 2021 Mar 17.
Biochem Pharmacol. 2021.
PMID: 33741332
Review.
Item in Clipboard
Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.
Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsée J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE.
Villacorte M, et al. Among authors: lernoux m.
Development. 2016 Jun 1;143(11):1958-70. doi: 10.1242/dev.134171. Epub 2016 Apr 11.
Development. 2016.
PMID: 27068110
Free PMC article.
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