Huang H - Search Results

1

Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia.

Dou L, Yan F, Pang J, Zheng D, Li D, Gao L, Wang L, Xu Y, Shi J, Wang Q, Zhou L, Shen N, Singh P, Wang L, Li Y, Gao Y, Liu T, Chen C, Al-Kali A, Litzow MR, Chi YI, Bode AM, Liu C, Huang H, Liu D, Marcucci G, Liu S, Yu L. Dou L, et al. Among authors: huang h. Nat Commun. 2019 Nov 7;10(1):5051. doi: 10.1038/s41467-019-12960-6. Nat Commun. 2019. PMID: 31699991 Free PMC article.

2

Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2.

Chen S, Bohrer LR, Rai AN, Pan Y, Gan L, Zhou X, Bagchi A, Simon JA, Huang H. Chen S, et al. Among authors: huang h. Nat Cell Biol. 2010 Nov;12(11):1108-14. doi: 10.1038/ncb2116. Epub 2010 Oct 10. Nat Cell Biol. 2010. PMID: 20935635 Free PMC article.

3

BRCA1 is a negative modulator of the PRC2 complex.

Wang L, Zeng X, Chen S, Ding L, Zhong J, Zhao JC, Wang L, Sarver A, Koller A, Zhi J, Ma Y, Yu J, Chen J, Huang H. Wang L, et al. Among authors: huang h. EMBO J. 2013 May 29;32(11):1584-97. doi: 10.1038/emboj.2013.95. Epub 2013 Apr 26. EMBO J. 2013. PMID: 23624935 Free PMC article.

4

BET bromodomain-mediated interaction between ERG and BRD4 promotes prostate cancer cell invasion.

Blee AM, Liu S, Wang L, Huang H. Blee AM, et al. Among authors: huang h. Oncotarget. 2016 Jun 21;7(25):38319-38332. doi: 10.18632/oncotarget.9513. Oncotarget. 2016. PMID: 27223260 Free PMC article.

5

SPOP mutation induces DNA methylation via stabilizing GLP/G9a.

Zhang J, Gao K, Xie H, Wang D, Zhang P, Wei T, Yan Y, Pan Y, Ye W, Chen H, Shi Q, Li Y, Zhao SM, Hou X, Weroha SJ, Wang Y, Zhang J, Karnes RJ, He HH, Wang L, Wang C, Huang H. Zhang J, et al. Among authors: huang h. Nat Commun. 2021 Sep 29;12(1):5716. doi: 10.1038/s41467-021-25951-3. Nat Commun. 2021. PMID: 34588438 Free PMC article.

6

SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition.

Ma J, Shi Q, Cui G, Sheng H, Botuyan MV, Zhou Y, Yan Y, He Y, Wang L, Wang Y, Mer G, Ye D, Wang C, Huang H. Ma J, et al. Among authors: huang h. Nat Commun. 2021 Oct 1;12(1):5779. doi: 10.1038/s41467-021-26049-6. Nat Commun. 2021. PMID: 34599168 Free PMC article.

7

Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer.

Ding D, Zheng R, Tian Y, Jimenez R, Hou X, Weroha SJ, Wang L, Shi L, Huang H. Ding D, et al. Among authors: huang h. Nat Commun. 2022 Oct 23;13(1):6311. doi: 10.1038/s41467-022-34024-y. Nat Commun. 2022. PMID: 36274096 Free PMC article.

8

Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis.

Ding D, Blee AM, Zhang J, Pan Y, Becker NA, Maher LJ 3rd, Jimenez R, Wang L, Huang H. Ding D, et al. Among authors: huang h. Nat Commun. 2023 Aug 3;14(1):4671. doi: 10.1038/s41467-023-40352-4. Nat Commun. 2023. PMID: 37537199 Free PMC article.

9

FOXO1 inhibits Runx2 transcriptional activity and prostate cancer cell migration and invasion.

Zhang H, Pan Y, Zheng L, Choe C, Lindgren B, Jensen ED, Westendorf JJ, Cheng L, Huang H. Zhang H, et al. Among authors: huang h. Cancer Res. 2011 May 1;71(9):3257-67. doi: 10.1158/0008-5472.CAN-10-2603. Epub 2011 Apr 19. Cancer Res. 2011. PMID: 21505104 Free PMC article.

10

LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer.

Wang D, Ding L, Wang L, Zhao Y, Sun Z, Karnes RJ, Zhang J, Huang H. Wang D, et al. Among authors: huang h. Oncotarget. 2015 Dec 1;6(38):41045-55. doi: 10.18632/oncotarget.5728. Oncotarget. 2015. PMID: 26516927 Free PMC article.

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