Menéndez JC - Search Results

1

Aza-CGP37157-lipoic hybrids designed as novel Nrf2-inducers and antioxidants exert neuroprotection against oxidative stress and show neuroinflammation inhibitory properties.

Michalska P, Tenti G, Satriani M, Cores A, Ramos MT, García AG, Menéndez JC, León R. Michalska P, et al. Among authors: menendez jc. Drug Dev Res. 2020 May;81(3):283-294. doi: 10.1002/ddr.21618. Epub 2019 Nov 6. Drug Dev Res. 2020. PMID: 31693218

2

Synthesis of polysubstituted, functionalized quinolines through a metal-free domino process involving a C4–C3 functional group rearrangement.

Ribelles P, Ramos MT, Menéndez JC. Ribelles P, et al. Among authors: menendez jc. Org Lett. 2012 Mar 16;14(6):1402-4. doi: 10.1021/ol300132e. Epub 2012 Feb 8. Org Lett. 2012. PMID: 22316241

3

New types of reactivity of α,β-unsaturated N,N-dimethylhydrazones: chemodivergent diastereoselective synthesis of functionalized tetrahydroquinolines and hexahydropyrrolo[3,2-b]indoles.

Sridharan V, Ribelles P, Estévez V, Villacampa M, Ramos MT, Perumal PT, Menéndez JC. Sridharan V, et al. Among authors: menendez jc. Chemistry. 2012 Apr 16;18(16):5056-63. doi: 10.1002/chem.201103562. Epub 2012 Mar 5. Chemistry. 2012. PMID: 22392600

4

One-pot access to a library of structurally diverse nicotinamide derivatives via a three-component formal aza [3 + 3] cycloaddition.

Tenti G, Ramos MT, Menéndez JC. Tenti G, et al. Among authors: menendez jc. ACS Comb Sci. 2012 Oct 8;14(10):551-7. doi: 10.1021/co300081k. Epub 2012 Sep 10. ACS Comb Sci. 2012. PMID: 22954155

5

New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury.

Tenti G, Parada E, León R, Egea J, Martínez-Revelles S, Briones AM, Sridharan V, López MG, Ramos MT, Menéndez JC. Tenti G, et al. Among authors: menendez jc. J Med Chem. 2014 May 22;57(10):4313-23. doi: 10.1021/jm500263v. Epub 2014 May 7. J Med Chem. 2014. PMID: 24754640

6

A heavy metal- and oxidant-free, one-pot synthesis of pyridines and fused pyridines based on a Lewis acid-catalyzed multicomponent reaction.

Raja VP, Tenti G, Perumal S, Menéndez JC. Raja VP, et al. Among authors: menendez jc. Chem Commun (Camb). 2014 Oct 21;50(82):12270-2. doi: 10.1039/c4cc01791a. Chem Commun (Camb). 2014. PMID: 24776752

7

B-ring-aryl substituted luotonin A analogues with a new binding mode to the topoisomerase 1-DNA complex show enhanced cytotoxic activity.

González-Ruiz V, Pascua I, Fernández-Marcelo T, Ribelles P, Bianchini G, Sridharan V, Iniesta P, Ramos MT, Olives AI, Martín MA, Menéndez JC. González-Ruiz V, et al. Among authors: menendez jc. PLoS One. 2014 May 15;9(5):e95998. doi: 10.1371/journal.pone.0095998. eCollection 2014. PLoS One. 2014. PMID: 24830682 Free PMC article.

8

ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.

Buendia I, Tenti G, Michalska P, Méndez-López I, Luengo E, Satriani M, Padín-Nogueira F, López MG, Ramos MT, García AG, Menéndez JC, León R. Buendia I, et al. Among authors: menendez jc. ACS Chem Neurosci. 2017 Jan 18;8(1):67-81. doi: 10.1021/acschemneuro.6b00181. Epub 2016 Nov 22. ACS Chem Neurosci. 2017. PMID: 27731633

9

Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia".

Buendia I, Tenti G, Michalska P, Méndez-López I, Luengo E, Satriani M, Padín-Nogueira F, López MG, Ramos MT, García AG, Menéndez JC, León R. Buendia I, et al. Among authors: menendez jc. ACS Chem Neurosci. 2017 Jan 18;8(1):210. doi: 10.1021/acschemneuro.6b00364. Epub 2016 Nov 23. ACS Chem Neurosci. 2017. PMID: 28095680 No abstract available.

10

Discovery of the first dual GSK3β inhibitor/Nrf2 inducer. A new multitarget therapeutic strategy for Alzheimer's disease.

Gameiro I, Michalska P, Tenti G, Cores Á, Buendia I, Rojo AI, Georgakopoulos ND, Hernández-Guijo JM, Teresa Ramos M, Wells G, López MG, Cuadrado A, Menéndez JC, León R. Gameiro I, et al. Among authors: menendez jc. Sci Rep. 2017 Mar 31;7:45701. doi: 10.1038/srep45701. Sci Rep. 2017. PMID: 28361919 Free PMC article.

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