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ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia.
Buendia I, Tenti G, Michalska P, Méndez-López I, Luengo E, Satriani M, Padín-Nogueira F, López MG, Ramos MT, García AG, Menéndez JC, León R. Buendia I, et al. Among authors: garcia ag. ACS Chem Neurosci. 2017 Jan 18;8(1):67-81. doi: 10.1021/acschemneuro.6b00181. Epub 2016 Nov 22. ACS Chem Neurosci. 2017. PMID: 27731633
Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry.
González-Lafuente L, Egea J, León R, Martínez-Sanz FJ, Monjas L, Perez C, Merino C, García-De Diego AM, Rodríguez-Franco MI, García AG, Villarroya M, López MG, de Los Ríos C. González-Lafuente L, et al. Among authors: garcia ag, garcia de diego am. ACS Chem Neurosci. 2012 Jul 18;3(7):519-29. doi: 10.1021/cn300009e. Epub 2012 Mar 26. ACS Chem Neurosci. 2012. PMID: 22860221 Free PMC article.
Novel sulfoglycolipid IG20 causes neuroprotection by activating the phase II antioxidant response in rat hippocampal slices.
Punzón E, García-Alvarado F, Maroto M, Fernández-Mendívil C, Michalska P, García-Álvarez I, Arranz-Tagarro JA, Buendia I, López MG, León R, Gandía L, Fernández-Mayoralas A, García AG. Punzón E, et al. Among authors: garcia alvarado f, garcia alvarez i, garcia ag. Neuropharmacology. 2017 Apr;116:110-121. doi: 10.1016/j.neuropharm.2016.12.016. Epub 2016 Dec 20. Neuropharmacology. 2017. PMID: 28007500 Free article.
New Nrf2-Inducer Compound ITH12674 Slows the Progression of Retinitis Pigmentosa in the Mouse Model rd10.
Campello L, Kutsyr O, Noailles A, Michalska P, Fernández-Sánchez L, Martínez-Gil N, Ortuño-Lizarán I, Sánchez-Sáez X, de Juan E, Lax P, León R, García AG, Cuenca N, Maneu V. Campello L, et al. Among authors: garcia ag. Cell Physiol Biochem. 2020 Feb 7;54(1):142-159. doi: 10.33594/000000210. Cell Physiol Biochem. 2020. PMID: 32028545 Free article.
Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia.
Lorrio S, Gómez-Rangel V, Negredo P, Egea J, Leon R, Romero A, Dal-Cim T, Villarroya M, Rodriguez-Franco MI, Conde S, Arce MP, Roda JM, García AG, López MG. Lorrio S, et al. Among authors: garcia ag. Neuropharmacology. 2013 Apr;67:403-11. doi: 10.1016/j.neuropharm.2012.12.001. Epub 2012 Dec 7. Neuropharmacology. 2013. PMID: 23228428
ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a novel acetylcholinesterase inhibitor with "calcium promotor" and neuroprotective properties.
Orozco C, de Los Rios C, Arias E, León R, García AG, Marco JL, Villarroya M, López MG. Orozco C, et al. Among authors: garcia ag. J Pharmacol Exp Ther. 2004 Sep;310(3):987-94. doi: 10.1124/jpet.104.068189. Epub 2004 Apr 26. J Pharmacol Exp Ther. 2004. PMID: 15111641
Addition to "ITH14001, a CGP37157-Nimodipine Hybrid Designed to Regulate Calcium Homeostasis and Oxidative Stress, Exerts Neuroprotection in Cerebral Ischemia".
Buendia I, Tenti G, Michalska P, Méndez-López I, Luengo E, Satriani M, Padín-Nogueira F, López MG, Ramos MT, García AG, Menéndez JC, León R. Buendia I, et al. Among authors: garcia ag. ACS Chem Neurosci. 2017 Jan 18;8(1):210. doi: 10.1021/acschemneuro.6b00364. Epub 2016 Nov 23. ACS Chem Neurosci. 2017. PMID: 28095680 No abstract available.
550 results