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Regulation of glucose and lipid metabolism in health and disease.
Chen L, Chen XW, Huang X, Song BL, Wang Y, Wang Y. Chen L, et al. Among authors: chen xw. Sci China Life Sci. 2019 Nov;62(11):1420-1458. doi: 10.1007/s11427-019-1563-3. Epub 2019 Oct 31. Sci China Life Sci. 2019. PMID: 31686320 Review.
mTOR-dependent upregulation of xCT blocks melanin synthesis and promotes tumorigenesis.
Li C, Chen H, Lan Z, He S, Chen R, Wang F, Liu Z, Li K, Cheng L, Liu Y, Sun K, Wan X, Chen X, Peng H, Li L, Zhang Y, Jing Y, Huang M, Wang Y, Wang Y, Jiang J, Zha X, Chen L, Zhang H. Li C, et al. Among authors: chen l, chen r, chen h, chen x. Cell Death Differ. 2019 Oct;26(10):2015-2028. doi: 10.1038/s41418-019-0274-0. Epub 2019 Feb 13. Cell Death Differ. 2019. PMID: 30760873 Free PMC article.
The physiological role of drug transporters.
Liang Y, Li S, Chen L. Liang Y, et al. Among authors: chen l. Protein Cell. 2015 May;6(5):334-50. doi: 10.1007/s13238-015-0148-2. Epub 2015 Mar 24. Protein Cell. 2015. PMID: 25797421 Free PMC article. Review.
Zoledronate dysregulates fatty acid metabolism in renal tubular epithelial cells to induce nephrotoxicity.
Cheng L, Ge M, Lan Z, Ma Z, Chi W, Kuang W, Sun K, Zhao X, Liu Y, Feng Y, Huang Y, Luo M, Li L, Zhang B, Hu X, Xu L, Liu X, Huo Y, Deng H, Yang J, Xi Q, Zhang Y, Siegenthaler JA, Chen L. Cheng L, et al. Among authors: chen l. Arch Toxicol. 2018 Jan;92(1):469-485. doi: 10.1007/s00204-017-2048-0. Epub 2017 Sep 4. Arch Toxicol. 2018. PMID: 28871336 Free PMC article.
Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans.
Che L, Chi W, Qiao Y, Zhang J, Song X, Liu Y, Li L, Jia J, Pilo MG, Wang J, Cigliano A, Ma Z, Kuang W, Tang Z, Zhang Z, Shui G, Ribback S, Dombrowski F, Evert M, Pascale RM, Cossu C, Pes GM, Osborne TF, Calvisi DF, Chen X, Chen L. Che L, et al. Among authors: chen l, chen x. Gut. 2020 Jan;69(1):177-186. doi: 10.1136/gutjnl-2018-317581. Epub 2019 Apr 6. Gut. 2020. PMID: 30954949 Free PMC article.
Inhibition of HSP90β Improves Lipid Disorders by Promoting Mature SREBPs Degradation via the Ubiquitin-proteasome System.
Zheng ZG, Zhang X, Liu XX, Jin XX, Dai L, Cheng HM, Jing D, Thu PM, Zhang M, Li H, Zhu J, Liu C, Xue B, Li Y, Chen L, Peng C, Zhu W, Wang L, Liu J, Li HJ, Li P, Xu X. Zheng ZG, et al. Among authors: chen l. Theranostics. 2019 Aug 12;9(20):5769-5783. doi: 10.7150/thno.36505. eCollection 2019. Theranostics. 2019. PMID: 31534518 Free PMC article.
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